9.19 Membrane Properties - Carrier-Mediated Transport Flashcards Preview

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Flashcards in 9.19 Membrane Properties - Carrier-Mediated Transport Deck (16):
1

saturability is a diagnostic characteristic of __________ transport

carrier-mediated transport

2

why is there saturability? (2)

1. finite number of transporters
2. each transporter has finite turnover

3

what are the two diagnostic characteristics of carrier-mediated transport?

1. saturability
2. selectivity

4

for carrier-mediated transport, flux is dependent on ___________. What is the equation for flux?

Jmax

J = (Jmax*[S])/(Kd + [S])

5

Kt is the substrate concentration at which ________________

half of the transporters are occupied

6

occurs when two or more substrates of a particular structure attempt to simultanously occupy the transporters. There is an increase in the Kt.

competitive inhibition

7

in competitive inhibition for a transporter, Kd is ________ and Jmax ___________

increased (takes more of original to half saturate)
stays the same

8

cocaine is an example of ________________ for serotonin

competitive inhibition

9

there is no ATP required in __________ __________ (membrane protein)

facilitated

10

CAN’T generate net flux against gradient:

facilitated diffusion

11

__________ __________ requires an energy source.

active transport

12

Develops and maintains transmembrane solute gradients

active transporters

13

in primary active transport, the immediate energy source is _______. in secondary active transport the immediate energy source is _______________.

ATP
existing trans-membrane ion gradients

14

the most common ion whose gradient is tapped into is ______

Na+

15

the inside of a cell has _______ K+ and _____ Na+

high K+
low Na+

16

what is an example of co-transport?

Na+/glucose transporter, uses Na+ concentration gradients to get glucose into the cell.