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Flashcards in Abnormal peds growth Deck (38)
1

T or F: normal growth is pulsatile

true

2

T or F: normal growth is seasonal

true

3

normal portionality for weight-to-height

2.3rd-97.7th percentile

4

body proportion (US/LS) is higher or lower in turners?

incr (longer US, shorter LS)

5

body proportion (US/LS) is higher or lower in marfan?

decr

6

FTT is based on decreased velocity of Weight or Length

WEIGHT

7

FTT is defined by (2)

1. weight under 2nd percentile
2. decr velocity of weight gain

8

how to determine if a child's growth is abnormally rapid

height-for-age curve deviated upwards across 2 major height % curves

9

what can you evaluate if there is evidence of accelerated growth

bone age

10

advanced bone age is ____% above chronological age

20%

11

most common overgrowth in infancy is

maternal diabetes

12

macrocephaly, frontal bossing, hypertelorism, intellectual disability, large at birth, advanced bone age, IFG1 normal

cerebral gigantism (sotos syndrome)

13

advanced bone age, rapid growth then slows, macrosomia, visceromegaly, macroglossia, omphalocele, hypoglycemia, hyperinsulinism, renal issues

beckwith-wiedemann syndrome

14

most common cause of tall state

familial tall stature

15

precocious puberty is more common in girls or boys

girls

16

types of precocious puberty

Central GDPP
peripheral GDIP

17

those with precocious puberty have ___bone age, ___epihpyseal closure

advanced bone age, early epiphyseal closure

18

most reliable measurement of growth hormone excess

IGFBP-3

19

long legs, reduced UL segment ratio, low sitting height (eunuchoid proportions)

sex hormone deficiency

20

mutation of ACTH receptor is primary or secondary adrenal insufficiency

primary adrenal insufficiency (high ACTH, low cortisol)

21

tall, obese, early onset puberty, low GH but normal IGF

exogenous obesity

22

what is the most common monogenic cause of human obesity?

melanocortin 4 receptor (MC4R)

23

hyperphagia, hyperinsulinemia, obese kid, preserved reproductive fxn

MC4R mutation

24

47XXY, long legs, short trunk, small testes, gynecomastia, learning disabled, bone age normal/delayed

klinefelter

25

how to tx klinefelter

testosterone

26

delayed motor/ language development, large teeth, tremor, ADHD, autism

47 XYY syndrome

27

lens subluxated upward

marfan

28

lens subluxated downward

homocystinuria

29

does marfans or homocysteinuria have risk for thrombotic events?

homocysteinuria

30

does marfans or homocysteinuria have risk for intellectual disability?

homocysteinuria

31

tall, AD, dysregulated GH, precocious pubterty, cafe au lait spots, hamartomas, gliomas

von recklinghausen disease (NF1)

32

madelung deformity of the forearm

turner syndrome

33

if you see a girl with short stature, what should be in your differential?

turner syndrome

34

obesity, severe hyperphagia, developmental delay, hypogonadism

prader-willi

35

how to tx prader-wili

GH

36

hypertelorism, downward slanting eyes, low ears, pectus excavatum, webbed neck, intellectual disability

noonan syndrome

37

how to tx noonan syndrome

GH

38

short trunk dwarfism, mostly affects spine

spondyloepiphyseal dysplasia