Absorption and Distribution of Drugs (L6&7) Flashcards Preview

Year 1 PHA > Absorption and Distribution of Drugs (L6&7) > Flashcards

Flashcards in Absorption and Distribution of Drugs (L6&7) Deck (8)
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1

What are the pathways of drug absorption?

Oral, Topical (antibiotics), Injection, Inhilation

2

How are drugs distributed throughout the body?

Absorption from small ph
Transport in blood- free or plama protein bound

3

What factors effect drug absorption?

Water solubility, lipid solubility, degree of ionisation, molecular weight, drugs metabolism

4

What factors affect drug distribution?

Perfusion of tissues

5

Describe the Michaelis-menten curve

h

6

Identify k and Vm

h

7

Describe the binding curve of low affinity ligand

h

8

What is the difference between efficacy and affinity

h