Flashcards in Absorption and Distribution of Drugs (L6&7) Deck (8)
What are the pathways of drug absorption?
Oral, Topical (antibiotics), Injection, Inhilation
How are drugs distributed throughout the body?
Absorption from small ph
Transport in blood- free or plama protein bound
What factors effect drug absorption?
Water solubility, lipid solubility, degree of ionisation, molecular weight, drugs metabolism
What factors affect drug distribution?
Perfusion of tissues
Describe the Michaelis-menten curve
Identify k and Vm
Describe the binding curve of low affinity ligand