ACP Questions #2 Flashcards Preview

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Flashcards in ACP Questions #2 Deck (552):
1

Viral cause of dendritic corneal lesions

Herpes simplex

2

Disease associated with blue sclerae

Osteogenesis imperfecta (accept iron deficiency anemia)

3

Medical term for finding at the margin of the cornea

Look up picture of Ciliary flush

4

Medical term for finding in the anterior chamber below the pupil

Look up picture of Hypopyon

5

Term that describes vision abnormality characterized by wavy and distorted lines

Metamorphopsia

6

Neuraminidase inhibitor that may cause bronchospasm

Zanamivir

7

Antibiotic for UTI associated with hyperkalemia and elevated serum creatinine in absence of renal failure

Trimethoprim-sulfamethoxazole (accept trimethoprim)

8

Vasopressin-receptor antagonist used to treat SIADH secretion

Conivaptan or tolvapatan (either)

9

Anti-tuberculosis drug that reduces blood level of oral contraceptives

Rifampin

10

Sunitinib and sorafenib inhibit this enzyme

Tyrosine kinase

11

Dental finding associated with bulimia

Enamel erosions

12

Eponym for respiratory pattern associated with metabolic acidosis

Kussmaul respiration

13

Name of sign describing inability to maintain a fixed posture associated with cirrhosis

Asterixis

14

Eponym for reflexively flexing knees and hips in response to passive flexion of the neck

Brudzinski sign

15

Device used to measure degree of exophthalmos

Exophthalmometer

16

An anaerobic gram-positive rod that produces two toxins causing mucosal damage

Clostridium difficile

17

Most common form of naturally occurring anthrax

Cutaneous anthrax

18

Treatment for severe parvovirus B19 infection in HIV patient

Intravenous immunoglobulin

19

Most common cause of fatal sporadic encephalitis in USA

Herpes encephalitis

20

Diagnosis consistent with CNS lesions that are dissemination in time and space

Multiple sclerosis

21

Antihypertensive drug class that reduces risk of second stroke regardless of blood pressure

Angiotensin-converting enzyme inhibitor

22

Dementia associated with prominent disinhibition and personality change

Frontotemporal dementia

23

The most common hereditary ataxia

Friedreich ataxia

24

Serum marker for vasoactive intestinal peptide tumor

Vasoactive intestinal peptide

25

Syndrome associated with rapid cell lysis, elevated uric acid, potassium, and phosphorus levels

Tumor lysis syndrome

26

Anatomical location of most carcinoid tumors

Ileum (accept small bowel)

27

Genetic mutation associated with MEN 2A

RET proto-oncogene (accept RET)

28

B Vitamin deficiency associated with carcinoid syndrome

Niacin (accept B3 or nicotinic acid)

29

The hallmark microscopic finding of microangiopathic hemolytic anemia

Red cell fragmentation (accept schistocytes)

30

The most common cause of thrombocytopenia during pregnancy

Gestational thrombocytopenia

31

Best screening test for factor V Leiden gene mutation

Protein C resistance

32

Anemia associated with increased sensitivity to complement binding

Paroxysmal nocturnal hemoglobinuria

33

Clotting factor deficiency most commonly associated with AL amyloidosis

Factor X

34

Developer of the Mini Mental State Exam

Folstein

35

First to describe breath sounds by auscultation

Laennec

36

Translation of belladonna

Beautiful lady (accept beautiful woman)

37

Term used to describe fever disappearing gradually with resolution of disease

Lysis

38

The "jennerian take" refers to this once common vaccination

Smallpox

39

Definitive diagnostic test to evaluate persistent, non-nephrotic proteinuria

Kidney biopsy

40

Antibody associated with Goodpasture syndrome

Anti-basement membrane antibody

41

Most likely diagnosis associated with acute renal injury, anemia and low-anion gap

Myeloma kidney (accept multiple myeloma)

42

Proteus mirabilis infection is associated with this type of crystal

Struvite (accept triple phosphate)

43

Syndrome of hyponatremia and hypovolemia associated with subarachnoid hemorrhage

Cerebral salt wasting (CSW) syndrome

44

Diagnosis associated with sentinel loop sign and colon cutoff sign

Acute pancreatitis

45

Best test to confirm current hepatitis C infection

HCV RNA level

46

Nutrition strategy for necrotizing pancreatitis that results in decreased infections

Enteral feedings

47

Biliary complication associated with AIDS

Sclerosing cholangiopathy

48

Cause of fever, pneumonitis, hepatitis, and colitis in transplant recipient

CMV infection

49

Domesticated animal bite associated with greatest risk of rabies in US

Cat

50

Indicated treatment for early localized Lyme disease during pregnancy

Amoxicillin

51

Diagnosis for trismus, unilateral tonsillar swelling, and uvula deviation

Peritonsillar abscess

52

Usual initial drug therapy for cryptogenic organizing pneumonia

Corticosteroids (accept prednisone)

53

Eponym for pulmonary nodules associated with rheumatoid arthritis

Caplan syndrome

54

Name for episodes of muscle extreme weakness in response to emotion

Cataplexy

55

Diagnosis for a subacute illness, eosinophilia and peripheral pulmonary infiltrates

Chronic eosinophilic pneumonia (must be "chronic" eosinophilic pneumonia)

56

Histological changes associated with beryllium exposure

Noncaseating granuloma

57

Device that reduces mortality in patients with cardiomyopathy and low ejection fraction

ICD (implantable cardioverter-defibrillator)

58

Characteristic second heart sound finding associated with atrial septal defect

Fixed splitting of S2

59

Phlebotomy improves heart failure associated with this metabolic disease

Hemochromatosis

60

Substitute for ACE inhibitor to treat heart failure during pregnancy

Hydralazine (accept hydralazine and nitrates)

61

Presumptive diagnosis for acute monoarthritis in a sexually active young adult

Disseminated gonococcal infection

62

Eponym applied to a painless nodule in the palmar aponeurosis

Dupuytren contracture

63

Cystic structure on wrist

Ganglion

64

Vasculitis associated with microaneurysms within the renal vasculature

Polyarteritis nodosa

65

Category of scleroderma most commonly associated with anti-Scl-70 antibodies

Diffuse cutaneous systemic scleroderma (accept diffuse scleroderma)

66

Most likely finding on brain imaging that contradicts use of thrombolytic therapy

Hemorrhage (accept bleeding, blood)

67

Syndromic diagnosis for this rash and ipsilateral facial paralysis

Ramsay Hunt syndrome (accept herpes zoster oticus)

68

Dementing syndrome with parkinsonism and hallucinations

Dementia with Lewy bodies

69

Primary brain tumor that disappears following corticosteroid therapy

Lymphoma

70

Syndrome of quadriplegia, paralysis of horizontal eye movements and bulbar muscles

Locked in syndrome

71

Eponym for pupils that fail to react to light but react to accommodation

Argyll Robinson pupil

72

Part of the macula that is the point of visual fixation

Fovea

73

Hallmark sign of early age-related macular degeneration

Drusen

74

Most likely organism causing this conjunctivitis [purulent]

N. gonorrhea

75

Proliferation of opaque fibrovascular conjunctival tissue medial to iris

Pterygium

76

Hematological complication of severe sleep apnea

Polycythemia (accept erythrocytosis)

77

Non-drug treatment to prevent post-phlebitic syndrome

Compression stockings

78

Syndrome of granulomatous vasculitis, asthma, eosinophilia, and fleeting pulmonary infiltrates

Churg-Strauss

79

Name given to pneumothorax associated with menstruation

Catamenial pneumothorax

80

Eponym for acute interstitial pneumonia

Hamman-Rich syndrome

81

Initial symptom of Rockey Mountain Spotted Fever

Fever

82

Measurement criterion for a positive PPD in injection drug users

≥ 10 mm

83

Infection associated with "sulfur granules" in draining sinuses

Actinomycosis

84

Name of this rash caused by Corynebacterium minutissimum

Erythrasma

85

A gram-negative infection in HIV patients that mimics Kaposi sarcoma

Bacillary angiomatosis (accept organism, Bartonella)

86

Most sensitive dipstick screening test for UTI

Leukocyte esterase

87

A potent intrinsic inhibitor of urine stone formation

Citrate

88

Adrenal cause of euvolemic hypoosmolality

Addision disease (accept hypocortisolism)

89

Name of acute kidney injury associated with a colonoscopy bowel preparation

Acute phosphate nephropathy

90

Acronym for syndrome of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin manifestations

POEMS syndrome

91

Most common cause of superior vena cava syndrome

Lung cancer

92

Cancer syndrome characterized by thousands of colonic polyps

Familial adenomatous polyposis

93

Cancer associated with new onset left sided varicocele and hydrocele

Renal cell carcinoma

94

Second most common cancer associated with hereditary nonpolyposis colorectal cancer

Endometrial (accept uterine)

95

Medical term for accentuated inspiratory fall in systolic pressure

Pulsus paradoxus

96

Maternal antibodies associated with neonatal congenital heart block

anti-Ro/SSA and anti-La/SSB (either antibody and either name for antibody)

97

Most common reperfusion arrhythmia associated with thrombolytic therapy

Accelerated idioventricular rhythm

98

Two drugs for "pill-in-the-pocket" treatment of atrial fibrillation

Flecainide and propafenone (name both)

99

Collective name for the malleus, incus, and stapes

The ossicles

100

Best physical examination test to rule out hearing loss

Whispered voice test

101

Tuning fork frequency recommended for Weber test

512 Hz

102

Vascular condition responsible for Lemierre syndrome

Internal jugular vein thrombophlebitis (accept jugular vein thrombophlebitis)

103

Clotting disorder characteristically associated with menorrhagia

von Willebrand disease

104

Mineral supplement that reduces PMS symptoms

Calcium

105

Eponym for an erythematous vulvar plaque that has a cancer association

Extramammary Paget disease (accept Paget disease)

106

Most common symptom of achalasia

Dysphagia

107

Most likely GERD-related esophageal diagnosis

Barrett esophagus [google picture]

108

Liver disease most closely associated with anti-LKM antibody

Autoimmune hepatitis

109

Diagnosis for diastase resistant, PAS-staining foamy macrophages and villous atrophy

Whipple disease

110

Factor that carries factor VIII in the circulation

von Willebrand factor

111

Four vitamin K dependent coagulation factors

II, VII, IX, and X (name all)

112

Intervention that decreases recurrent stroke in sickle cell disease

Exchange transfusion

113

Cause of splenomegaly and hepatomegaly in myelofibrosis (myeloid metaplasia)

Extramedullary hematopoiesis

114

Prescription that prolongs life in hypoxic COPD

Supplemental oxygen

115

Severe α1-antitrypsin deficiency is a risk factor for this non-malignant liver disease

Cirrhosis

116

Classification of asthma that recurs 2 days/week or nocturnal symptoms twice/month

Mild persistent asthma

117

Stage of sleep during which hypoventilation is most prominent

REM (accept rapid eye movement)

118

Best test to differentiate sleep apnea from obesity hypoventilation syndrome

Daytime (awake) ABG (accept PCO2)

119

MI location most commonly associated with papillary muscle rupture

Inferior wall

120

Mechanism responsible for the pacemaker syndrome

Atrioventricular dyssynchrony (accept dyssynchrony)

121

The most common symptom of scabies

Itching

122

Common drug that exacerbates chronic idiopathic urticaria

Aspirin (accept NSAIDs)

123

Topical drug treatment for superficial basal cell carcinoma

Imiquimod or 5-fluorouracil (either acceptable)

124

Most frequent side-effect of isotretinoin

Dry lips and eyes (accept dry skin)

125

Anatomical location of pancreatic cancer associated with obstructive jaundice

Head of pancreas

126

Second most common cause of cancer death in the U.S.

Colorectal cancer

127

Surgical intervention associated with increased risk of renal cancer

Renal transplantation

128

Stage classification for a patient with small-cell lung cancer involving both lungs

Extensive (accept stage IV)

129

A tripartite benign tumor composed of blood vessel, muscle, and fat elements

Angiomyolipoma (accept hamartoma)

130

Device that prevents 50% of unintentional carbon monoxide poisonings

Carbon monoxide detector

131

Time after acetaminophen overdose when aminotransferase levels become elevated

36 hours (accept any answer within 24 to 72 hours range)

132

Cause of bright red venous blood due to mitochondria poisoning

Hydrogen cyanide

133

Acute metal exposure associated with abdominal colic, headache, and fatigue

Lead

134

Stimulation of this parasympathetic receptor produces salivation, bronchorrhea, and bronchospasm

Muscarinic

135

Syndrome characterized by BMI >35 and PCO2 >45 torr

Obesity hypoventilation (Pickwickian)

136

Look up picture of...

Bilateral hilar lymphadenopathy (accept hilar lymphadenopathy)

137

Position that relieves platypnea

Lying flat

138

Disease characterized by arthritis, carditis and erythema marginatum

Rheumatic fever

139

Syndrome of purpura, arthritis, peripheral neuropathy, and hepatitis C infection

Cryoglobulinemic vasculitis (accept cryoglobulinemia)

140

Schober test is associated with this condition

Ankylosing spondylitis

141

Rheumatoid arthritis complication producing pain in the arms, hyperreflexia, and hypertonia

Atlantoaxial subluxation (accept AAS or cervical spine disease)

142

Next test for high probability subarachnoid hemorrhage but normal CT

Lumbar puncture

143

Cause of painless weakness, muscle atrophy, and upper and lower motor neuron signs

Amyotrophic lateral sclerosis

144

Syndrome manifested by motor function limited to blinking or moving eyes vertically

Locked-in syndrome

145

Type of weight loss diet that can worsen symptoms of patients treated for Parkinson's disease

High protein

146

Neurological term that describes inability to correctly draw a clock face

Constructional apraxia

147

Most useful diagnostic test for superior vena cava syndrome

Contrast CT

148

Most common cancer causing palpable gall bladder and jaundice

Pancreatic cancer

149

Predictive score derived by summing the two most prevalent histological grades of prostate adenocarcinoma

Gleason score

150

Complication associated with bisphosphonate infusion

Osteonecrosis of jaw

151

Inherited syndrome of breast cancer, brain tumors, soft tissue sarcomas, and leukemia

Li-Fraumeni syndrome

152

Look up picture of..

Kyphoscoliosis

153

Name for fever that exacerbates every 48 hours

Tertian fever

154

Condition associated with Austin-Flint murmur

Aortic regurgitation

155

Name of test that measures tear production

Schirmer's test

156

The most common cause of acute pancreatitis in the U.S.

Gallstones

157

Diagnostic test of choice for Zenker diverticulum

Barium swallow

158

Non-malignant diagnosis associated with dysphagia for solids and liquids and regurgitation

Achalasia

159

Enzyme deficiency in Gilbert syndrome

Glucuronosyltransferase

160

Gene mutation associated with familial adenomatous polyposis

APC gene

161

Look up bone marrow picture of..

Aplastic anemia

162

Look up picture of for thrombocytopenia

Platelet clumping (accept pseudothrombocytopenia)

163

Name the most common anatomical site for occurrence of warfarin skin necrosis

Limbs and breasts (accept either answer)

164

Treatment for ITP that is used only in Rh(+) patients

Anti-Rho(D)

165

A metalloproteinase that cleaves large multimers of von Willebrand factor

ADAMTS 13

166

Diagnostic test of choice for Zenker diverticulum

Barium swallow

167

Non-malignant diagnosis associated with dysphagia for solids and liquids and regurgitation

Achalasia

168

Enzyme deficiency in Gilbert syndrome

Glucuronosyltransferase

169

Gene mutation associated with familial adenomatous polyposis

APC gene

170

Look up bone marrow picture of..

Aplastic anemia

171

Look up picture of for thrombocytopenia

Platelet clumping (accept pseudothrombocytopenia)

172

Name the most common anatomical site for occurrence of warfarin skin necrosis

Limbs and breasts (accept either answer)

173

Treatment for ITP that is used only in Rh(+) patients

Anti-Rho(D)

174

A metalloproteinase that cleaves large multimers of von Willebrand factor

ADAMTS 13

175

Common drug poisoning responsible for aminotransferase levels >5000 U/L

Tylenol toxicity

176

Diagnosis associated with anion gap acidosis, osmolar gap, and urinary calcium oxalate crystals

Ethylene glycol poisoning

177

Gas poisoning associated with flame-shaped retinal hemorrhages

Carbon monoxide

178

Alcohol poisoning associated with increased osmolar gap but a normal anion gap

Isopropyl alcohol

179

Fish responsible for ciguatera fish poisoning

Groupers, parrot fish, snappers, mackerel, moray eels, and barracudas (name only 1)

180

Type of hypersensitivity reaction associated with IgE antibody and allergen

Type I hypersensitivity

181

Diagnosis for fever, adenopathy, and arthralgias following drug exposure

Serum sickness

182

Intravenous epinephrine concentration used for anaphylactic shock

1:10,000

183

Disease associated with Jarisch-Herxheimer reaction

Syphilis

184

Type of hypersensitivity reaction associated with contact dermatitis

Type IV hypersensitivity

185

Mental health disorder associated with increased risk for recurrent hospitalization after MI

Depression

186

Disorder associated with nightmares, flashbacks, or intrusive memories

Posttraumatic stress disorder

187

Common sexual complication associated with SSRI therapy

Anorgasmia

188

Condition characterized by excessive worry on most days for at least 6 months

Generalized anxiety disorder (accept anxiety)

189

Drug used in treatment of alcohol-dependent patients that are still drinking

Naltrexone

190

Clinical features of B12 deficiency can be acutely precipitated by this anesthetic agent

Nitrous oxide

191

Mechanism by which Graves disease causes blindness

Compression of optic nerve

192

Cause of giant papillary conjunctivitis

Allergy

193

Eponym applied to pupil that has an afferent pupillary defect

Marcus Gunn pupil

194

Systemic disease with highest prevalence of anterior uveitis

Behçet's disease

195

Blocks peripheral metabolism of levodopa

Carbidopa

196

A common antibiotic that increases serum creatinine without altering GFR

Trimethoprim (accept Bactrim or Septra or TMP)

197

Antiemetic that is now used for immunosuppressant properties

Thalidomide

198

Drug is a direct renin inhibitor

Aliskiren

199

Diagnosis for respiratory distress following removal of a central venous catheter

Venous air embolism (accept air embolism)

200

Time after radiation therapy that radiation pneumonitis is most likely to become symptomatic

1 to 3 months (any answer within range)

201

Radiographic hallmark of asbestos exposure

Calcified pleural plaques and diaphragmatic plaques (accept either or both answers)

202

Altitude sickness characterized by mental status changes and ataxia

High altitude cerebral edema (accept HACE or cerebral edema)

203

Cause of shortness of breath and pleuritic chest pain at beginning of menstruation

Catamenial pneumothorax (accept endometriosis or pleural endometriosis)

204

Recommended vitamin supplementation for any chronic hemolytic anemia

Folic acid

205

Cause of physiological anemia associated with normal pregnancy

Increased plasma volume

206

Red blood cell membrane receptor for human parvovirus 19

P antigen receptor

207

STD characterized by painful, exudative genital ulcer and painful regional lymphadenopathy

Chancroid

208

Cause of all clinical variants of Kaposi sarcoma

Human herpesvirus-8 (or Kaposi's sarcoma herpes virus, or KSHV)

209

Classical bacterial cause of cellulitis after sea water exposure

Vibrio vulnificus

210

The incubation period for smallpox

12 to 17 days (accept any value within range)

211

Implication of new first degree heart block associated with aortic valve endocarditis

Abscess of annular ring

212

Most likely infectious cause of Bell palsy

Herpes simplex

213

Asymmetric arm swing is an early physical finding of this movement disorder

Parkinson's disease

214

Initial multiple sclerosis disease pattern for most patients

Relapsing-remitting

215

Cause of loss of feeling of the lateral thigh.

Meralgia paresthesia (accept lateral femoral cutaneous nerve syndrome)

216

Class of drug that worsens aortic regurgitation by prolonging diastole

β-blocker

217

INR target to reduce stroke in nonvalvular atrial fibrillation

2-3

218

Echocardiographic mitral valve finding associated with acute aortic regurgitation

Early closure of the mitral valve

219

Implication of new first degree heart block associated with aortic valve endocarditis

Abscess of annular ring

220

Term for age-related hearing loss

Presbycusis

221

Category of disease causing abnormal Rinne test result

Conductive hearing loss

222

Most likely diagnosis associated with whitish, middle ear mass

Cholesteatoma

223

Diet for initial treatment for Meniere's disease

Low Salt Diet

224

Syndrome of sore throat, fever, sepsis, and unilateral neck swelling

Lemierre syndrome

225

Syndrome of elevated fasting gastrin level and elevated basal acid output

Gastrinoma (Zollinger-Ellison syndrome)

226

Collagenous colitis and lymphocytic colitis are subtypes of this colitis

Microscopic colitis

227

Eponym for aberrant submucosal vessel causing obscure UGI bleeding

Dieulafoy lesion

228

Most likely diagnosis causing generalized pruritus in the setting of inflammatory bowel disease

Primary sclerosing cholangitis

229

Pulmonary syndrome in young women with recurrent pneumothorax and airflow obstruction

Pulmonary lymphangioleiomyomatosis (LAM)

230

Parotid gland finding associated with bulimia

Parotid enlargement

231

The Finkelstein test is positive in this condition

de Quervain's tenosynovitis

232

Name to describe fever with temperature variation ≥1.4 °C daily

Hectic fever (accept spiking fever)

233

Titubation is a sign of disease in this part of the brain

Cerebellum (head and/or trunk tremor)

234

Syndrome of abnormal sensations in the legs and restlessness relieved by movement

Restless leg syndrome

235

Lymph node finding on chest x-ray suggestive of pulmonary silicosis

"Egg shell" calcification

236

Most likely tumor syndrome characterized by wheezing, flushing and diarrhea

Carcinoid syndrome

237

Pulmonary syndrome in young women with recurrent pneumothorax and airflow obstruction

Pulmonary lymphangioleiomyomatosis (LAM)

238

Turner's syndrome karyotype

XO

239

Urinary albumin excretion defining microalbuminuria

30 to 300 mg (accept ≥ 30 mg)

240

Obesity treatment associated with decreased overall mortality

Bariatric surgery

241

Dermal accumulation of this substance accounts for the cutaneous findings of myxedema

Mucopolysaccharides

242

Syndrome of hypothalamic hypogonadism and anosmia

Kallmann's syndrome

243

Name of model that predicts risk of breast cancer

Gail model

244

Radiograph that helps establish cause of bilateral ankle periarthritis and erythema nodosum

Chest x-ray (Lofgren's syndrome)

245

Eponym for hereditary disorder of renal carcinoma, pheochromocytoma, and neuroendocrine pancreatic tumors

von Hippel?Lindau disease

246

Meaning of 2 in CHADS2 mnemonic

Stroke or TIA awarded 2 points

247

Diagnostic test of choice for patients with acute monarticular arthritis

Arthrocentesis (accept analysis of synovial fluid including synovial fluid leukocyte count, gram stain, culture)

248

Google picture of..

Bouchard's nodes

249

Diagnosis for oligoarthritis of knees, ankles, or wrists associated with new periosteal bone formation

Hypertrophic osteoarthropathy

250

Target level for uric acid in the treatment of tophaceous gout

<6 mg/dL

251

Radiograph that helps establish cause of bilateral ankle periarthritis and erythema nodosum

Chest x-ray (Lofgren's syndrome)

252

The most common disorder of erythrocyte metabolism

Glucose 6-phosphate dehydrogenase (G6PD) deficiency

253

Meaning of 2 in CHADS2 mnemonic

Stroke or TIA awarded 2 points

254

Location of blood vessels most often involved in Moyamoya disease

Cerebrovascular (accept brain, intracranial)

255

Ranolazine produces this ECG change

Increases QT interval

256

Most common cause of hospital admission for sickle cell anemia

Pain crisis

257

Genetic transmission of von Willebrand's disease

Autosomal dominant disorder

258

Cause of acute renal failure associated with oral sodium phosphate bowel cleansing preparations

Acute phosphate nephropathy

259

The most common disorder of erythrocyte metabolism

Glucose 6-phosphate dehydrogenase (G6PD) deficiency

260

Smear with smudge smell.

Chronic myeloid leukemia (accept CML)

261

Eponym for a renal-pulmonary vasculitis syndrome and positive anti-glomerular basement membrane antibody

Goodpasture syndrome

262

Category of acute kidney injury associated with muddy brown casts

ATN (acute tubular necrosis)

263

Syndrome of normal anion-gap metabolic acidosis, hypokalemia, urine pH > 5.5 and renal stones

Type 1 (distal) renal tubular acidosis (RTA alone not acceptable)

264

Neurological complication of overly rapid correction of serum sodium in severe hyponatremia

Pontine and extrapontine myelinolysis (accept either, accept myelinolysis, central pontine myelinolysis or osmotic demyelination)

265

Cause of acute renal failure associated with oral sodium phosphate bowel cleansing preparations

Acute phosphate nephropathy

266

First diagnostic test for abnormal uterine bleeding

Pregnancy test

267

Name of a low-powered magnification device for detecting invasive cervical cancer

Colposcope

268

The most common etiology of hirsutism and oligomenorrhea

Polycystic ovary syndrome (accept Stein-Leventhal syndrome)

269

Blood test for women with headache, oligomenorrhea and galactorrhea

Prolactin level

270

Diabetic drug that increases ovulation rates in women with polycystic ovary syndrome

Metformin

271

A multifocal, angioproliferative tumor presenting as purple cutaneous papules

Kaposi sarcoma

272

Criterion for a positive PPD in patients receiving a tumor necrosis factor-alpha inhibitor

≥5 mm

273

CNS disease caused by polyomavirus JC in HIV patients

Multifocal leukoencephalopathy

274

Disease associated with this x-ray and infection with Taenia solium [brain cyst]

Neurocysticercosis (accept cysticercosis)

275

Syndrome of nasal congestion, sneezing and rhinorrhea triggered by allergen

Allergic rhinitis

276

Most common viral infection associated ampicillin-induced maculopapular rash

Epstein-Barr (accept infectious mononucleosis)

277

Life-threatening complication associated with IV immunoglobulin in IgA deficiency

Anaphylaxis

278

Most common plant cause of a type IV hypersensitivity reaction

Poison ivy or poison oak (either)

279

Diagnosis for unilateral findings of constricted pupil, facial dryness, and ptosis

Horner syndrome

280

Recommended point in time to begin screening for microalbuminuria in type 1 diabetes

5 years after diagnosis

281

Thyroid disease associated with anti-thyroid peroxidase antibody

Hashimoto's thyroiditis

282

Syndrome of autoimmune thyroid disease, type 1 diabetes, and Addison disease

Autoimmune polyglandular syndrome type II (accept autoimmune polyglandular syndrome or Schmidt's syndrome)

283

Look up x-ray of..

Paget disease (accept osteitis deformans)

284

Most likely cause of secondary amenorrhea following uterine curettage

Asherman syndrome (accept uterine synechiae)

285

Diagnosis for young, obese woman with headache, papilledema, and normal brain MRI

Benign intracranial hypertension (pseudotumor cerebri)

286

This finding is associated with von Recklinghausen disease [google image]

Neurofibroma

287

Part of the brain affected by the "locked-in syndrome"

Base of pons (accept pons)

288

Cause of symptomatic carotid artery stenosis and angiogram showing "string of beads" image

Fibromuscular dysplasia

289

Classification of asthma that recurs 2 days/week or nocturnal symptoms twice/month

Mild persistent asthma

290

Stage of sleep during which hypoventilation is most prominent

REM (accept rapid eye movement)

291

Best test to differentiate sleep apnea from obesity hypoventilation syndrome

Daytime (awake) ABG (accept PCO2)

292

Vasculitis associated with antiglomerular basement membrane antibodies

Goodpasture's syndrome

293

Next test when RPR serologic test is reactive

A treponemal-specific test (i.e., FTA-ABS, TP-PA)

294

Extra-pulmonary Pneumocystis infection is mainly associated with this disease

AIDS (accept HIV disease)

295

Microbiological stain for tuberculosis

Ziehl-Neelsen or Kinyoun (either)

296

Wild animal bite associated with greatest risk of rabies in US

Bat

297

Duration of rifampin treatment for latent pulmonary TB

4 months

298

Acid-base abnormality associated with renal tubular acidosis

Non-anion gap metabolic acidosis

299

Besides casts, microscopic urinalysis finding specific for glomerulonephritis

Dysmorphic red blood cells

300

Non-drug treatment for acute renal failure due to cryoglobulinemia

Plasmapheresis

301

Drug that suppresses hematuria associated with BPH

Finasteride

302

Neurological term that describes inability to correctly draw a clock face

Constructional apraxia

303

Initial imaging choice to diagnose uterine fibroids

Initial imaging choice to diagnose uterine fibroids

304

Best test to confirm premature ovarian failure

FSH level (accept FSH and LH)

305

This test and cervical cytology increases the accuracy of cervical cancer screening

HPV testing

306

Drug class that increases bladder internal sphincter tone and outflow resistance

α-Adrenergic agonists (accept phenylpropanolamine)

307

Drug class effective for hot flashes in estrogen receptor positive breast cancer

SSRI

308

Name of inclusion bodies in G6PD def

Heinz Body

309

Hematological diagnosis in asymptomatic young man [target cells on smear]

Thalassemia trait (accept thalassemia)

310

First vital sign to be routinely recorded in the hospital

Temperature

311

Test that used blood pressure cuff to measure capillary fragility

Rumpel-Leed test

312

Egophony was originally described sounding like this animal sound

Bleating of a goat (accept goat)

313

First physician to describe clubbing of the fingers

Hippocrates

314

Diagnosis for otalgia, ear discharge, and pruritus

Otitis externa

315

Clinical examination maneuver with best sensitivity and specificity to diagnose otitis media in children

Pneumatic otoscopy

316

A mass composed of keratinized epithelial debris located in the middle ear

Cholesteatoma

317

Class of drug used to treat Meniere's disease

Diuretics (accept betahistine hydrochloride)

318

Cause of discharging sinus on the point of the chin and toothache

Root abscess of lower incisors (accept dental abscess)

319

AST/ALT ratio associated with alcoholic hepatitis

>2.0 (accept 2.0)

320

Antibody associated with primary biliary cirrhosis

Antimitochondrial antibody

321

Non-malignant condition associated with dysphagia with cold or carbonated beverages

Achalasia (also accept neuromuscular dysfunction)

322

Condition predisposing to sclerosing cholangiopathy caused by cryptosporidium

AIDS (accept HIV disease)

323

Most common reason why stools float

Fecal gas (not fat)

324

Cardiac diagnosis associated with rib notching on chest x-ray

Aortic coarctation

325

Diagnosis for acute chest pain and new diastolic murmur

Ascending aortic dissection (accept aortic dissection)

326

Palpation of this neck tumor produces bradycardia

Carotid body tumor (accept Glomus Tumor)

327

Diagnosis for regular tachycardia associated with intermittent jugular cannon waves

Ventricular tachycardia

328

Google picture of..

Bullous pemphigoid

329

Cause of tetany following thyroid surgery

Hypocalcemia (accept hypoparathyroidism)

330

Bone mass T score diagnostic of osteoporosis

< - 2.5 (accept - 2.5)

331

Physical examination finding most effective in ruling out hyperthyroidism

Absence of goiter (- LR = 0.1)

332

Karyotype associated with androgen resistance syndrome

XY

333

Diagnosis associated with physical sign called accoucheur's hand

Hypocalcemia (sign is carpal spasm)

334

Diagnosis for hypotension and edema involving skin, oropharynx, genitalia

Angioedema

335

Most common gastrointestinal infection associated with IgA deficiency

Giardiasis

336

Best initial screening test for recurrent Neisserial infections

CH50 (accept total hemolytic complement or terminal complement components)

337

Type of hypersensitivity reaction associated with a positive PPD test

Type IV hypersensitivity

338

Endocrine deficiency associated with nasal congestion and rhinitis

Thyroid (accept hypothyroidism)

339

Non-drug therapy that decreases risk for ventilator associated pneumonia

Elevation of bed to 45 degrees (accept elevation of head of bed)

340

Systemic disease associated with shrinking lung syndrome

Systemic lupus erythematosus (SLE)

341

Bouchard's nodules involved these joints

Proximal interphalangeal joints (accept PIP joints)

342

Name of finding in patient with rheumatoid arthritis

Rheumatoid nodule [google picture]

343

Name for physical finding affecting left 3rd and 4th digits

Dactylitis [google picture]

344

Antibody most specific for diffuse systemic sclerosis

Anti-Scl-70 antibodies

345

Gastrointestinal symptom that predicts a complicated course in polymyositis

Dysphagia

346

Most likely diagnosis in person with normal vision [ red conjunctiva]

Conjunctivitis

347

Most likely cause of this opacity [white mass inside eye]

Cataract

348

Term for inflammation of the iris and ciliary body

Anterior uveitis (accept uveitis)

349

Blinding disease of the elderly associated with a chronic blistering skin disease

Ocular cicatricial pemphigoid (accept pemphigoid)

350

Antibiotic class associated with tooth discoloration in young children

Tetracycline

351

A topical cream that depletes substance P

Capsaicin

352

Most common cause of hyperuricemia in renal transplant patients

Cyclosporine therapy

353

Cisplatin causes significant depletion of these two cations

Magnesium and calcium

354

Growth factor for T-cells and natural killer cells

IL-2 (interleukin-2)

355

Condition defined by daily urinary albumin excretion of 30 to 300 mg

Microalbuminuria

356

Non-drug treatment for acute renal failure due to Goodpasture's syndrome

Plasmapheresis

357

Most common cause of urine eosinophilia

Acute interstitial nephritis

358

Diagnosis associated with hematuria and nephritic urine sediment within days of URI

IgA nephropathy

359

Diastolic pressure threshold to withhold rt-PA for acute stroke

> 110 mm Hg (accept 110 mm Hg)

360

Neurological disorder associated with this skin finding [dermatofibroma]

Neurofibromas

361

Most common cause of acquired spastic paresis in adults

Osteoarthritis of cervical spine (accept osteoarthritis)

362

Most common sign of renal cancer

Hematuria

363

Mutations of this gene causes familial adenomatous polyposis

APC gene

364

Cancer diagnosis classically associated with pain after drinking alcohol

Hodgkin's disease (accept lymphoma)

365

Malignant cause of black cerebrospinal fluid

Malignant melanoma

366

Drug that causes regression of erythroplakia

Isotretinoin

367

Best drug for Trichomonas vaginitis during pregnancy

Metronidazole

368

Amsel's criteria are used to diagnose this disorder

Bacterial vaginosis

369

Three anatomical areas associated with "Paget's disease"

Breast (accept nipple), vulva, and bone

370

The major high-risk HPV types for cervical cancer

16, 18

371

"Gold standard" for diagnosing iron deficiency anemia

Bone marrow aspirate for iron

372

Diagnosis that is confirmed by the cellular inclusion [Auer Rod]

Acute myeloid leukemia (accept myeloid leukemia, AML)

373

Antibody associated with transfusion-related acute lung injury

Granulocyte antibody

374

A platelet lowering drug that is less leukemogenic than hydroxyurea

Anagrelide

375

Prolactin inhibitory hormone secreted by the hypothalamus

Dopamine

376

Onset of action of lispro/aspart insulins

15 minutes (accept any value within range 10-20 minutes)

377

Effect of placenta on circulating thyroxine

Increased metabolism

378

Incretin mimetic agent that enhances glucose-dependent insulin secretion

Exenatide

379

Ethnic group most commonly affected by thyrotoxic periodic paralysis

Asians

380

Type of hearing loss associated with otitis media

Conductive

381

Tuning fork test that is most predictive of conductive hearing loss

Rinne (+LR = 16.8)

382

Disease treated with otolith repositioning maneuver

Benign positional vertigo

383

Anatomical change associated with ozena

Nasal mucosal atrophy (accept atrophic rhinitis)

384

Condition associated with endolymphatic hydrops

Meniere's disease

385

Streptococcus organism associated with colon cancer

S. bovis

386

Criterion for a positive PPD in patients with HIV

5 mm

387

New "gold standard" for gonorrhea performed on vaginal or urine specimens

NAAT

388

Total duration of antibiotic treatment for inhalational anthrax

60 days

389

Diarrhea associated with curved, gram-negative rods arranged as "seagull wings"

Campylobacter jejuni

390

Diagnosis for nasal congestion and rhinorrhea triggered by allergen exposure

Allergic rhinitis

391

Most common metal causing a type IV hypersensitivity reaction

Nickel

392

Anaphylaxis treatment for patient on beta-blocker not responding to epinephrine

Glucagon

393

Drug that reduces mortality by irreversibly inhibiting thromboxane A2

Aspirin

394

Most common cause of palpable pulsus bisferiens

Aortic regurgitation

395

Diagnosis associated with "water-wheel" sound on cardiac auscultation

Air embolism

396

Skin rash associated with Lyme disease

Erythema chronicum migrans (accept erythema migrans)

397

Most likely diagnosis for this transient, very itchy skin finding [ image]

Annular urticaria (accept urticaria) [google photo]

398

Diagnosis of this allergic skin condition [ image ]

Fixed drug eruption [google photo]

399

The three classic percussion sounds

Resonance, tympany, dullness (must name all three)

400

Most common cause of unilateral decreased vocal fremitus

Pneumothorax, hydrothorax (pleural effusion) (accept either answer)

401

Bilirubin threshold detectable by 70% of physicians on physical examination

2.5 - 3 mg (any answer in this range)

402

Medical name for skin tags

Acrochordons

403

Cardiac disease associated with systolic pulsation of the uvula (Muller's sign)

Aortic regurgitation

404

A sickle cell complication characterized by fever, chest pain, and pulmonary infiltrates

Acute chest syndrome

405

The principal treatment modality for TTP

Plasma exchange (accept plasmapheresis)

406

Most common ECG finding associated with amyloidosis

Decreased voltage

407

Name for thyrotoxicosis related proptosis, ocular paresis, and optic neuropathy

Grave's ophthalmopathy

408

Diagnosis associated with retinal microaneurysms, dot hemorrhages, and macular edema

Diabetic retinopathy (accept diabetes)

409

Name for continuous low-pitched supraclavicular sound which disappears with pressure to the veins above the stethoscope

Venous hum

410

Eponym for uveitis, parotid enlargement, and fever seen in sarcoidosis

Heerfordt's syndrome

411

Name for systolic sound heard with stethoscope over the breasts in late pregnancy

Mammary souffle

412

Eponym for deforming osteoarthritis of PIP joints

Bouchard's nodules

413

First-line drug class to preserve renal function in scleroderma renal crisis

Angiotensin-converting enzyme inhibitor

414

Diagnosis for self-limited, symmetric polyarthritis associated with "slapped cheeks" disease

Parvovirus (fifth disease)

415

Eponym for nonerosive, deforming arthritis in SLE

Jaccoud's arthritis

416

Type of urinary incontinence associated with coughing

Stress incontinence

417

Most likely cause of dysfunctional bleeding associated with irregularly-shaped uterus

Uterine fibroids

418

Common benign mass at the vaginal introitus

Bartholin's cyst

419

Chronic, idiopathic vulvar syndrome characterized by burning, stinging, and irritation

Vulvodynia

420

Chronic, diffuse vulvar condition characterized by hypopigmentation and thin "parchment paper" skin

Lichen sclerosus

421

Most likely etiology of central visual loss of the elderly

Age-related macular degeneration (accept macular degeneration)

422

Most common cardiac complication of cataract surgery

Bradyarrhythmias and hypotension (either acceptable)

423

Benign deposits of subepithelial tissue confined to the medial or lateral conjunctiva

Pinguecula

424

Class of drug that inhibits sodium reabsorption in the ascending loop of Henle

Loop diuretics

425

An idiosyncratic reaction to antipsychotic medications producing high fever

Neuroleptic malignant syndrome

426

Antibiotic that causes "red-man" syndrome

Vancomycin

427

Generic term for both nicotinic acid and nicotinamide

Niacin

428

Anti-viral drug that also stimulates dopamine release and blocks dopamine reuptake

Amantadine

429

Behavioral condition causing acquired shortened height of molars

Bruxism (accept teeth grinding)

430

Histological finding associated with erythroplakia

Carcinoma in situ

431

Most common cause of episodic tinnitus

Age-related hearing loss (accept presbycusis)

432

Eponym for internal jugular vein septic thrombophlebitis following a sore throat

Lemierre syndrome

433

Most common presenting sign of ampulla of Vater cancer

Jaundice

434

Histological finding associated with Barrett's esophagus

Intestinal metaplasia (accept columnar metaplasia, adenomatous hyperplasia)

435

Color of gallstones associated with hemolysis

Black

436

Autoimmune gastrointestinal disease associated with IgA deficiency

Celiac sprue

437

Syndrome of recurrent cholangitis and hepatolithiasis in Southeast Asians

Recurrent pyogenic cholangitis

438

Disease with chest x-ray described as "lower zone emphysema"

Alpha-1-antitrypsin deficiency

439

Disease with chest x-ray described as "photographic negative of pulmonary edema"

Chronic eosinophilic pneumonia

440

Syndrome of familial, prion-related progressive insomnia and in death within a year

Fatal familial insomnia

441

Treatment to prevent hemochromatosis associated hepatocellular carcinoma

Phlebotomy

442

Eponym for gastroesophageal mucosal ring associated with dysphagia

Schatzki's ring

443

Chronic bacterial carrier state associated with gallbladder cancer

Salmonella typhi (accept typhoid)

444

Cause of isolated gastric varices following acute pancreatitis

Splenic vein thrombosis

445

Eponym for obstruction of the proximal duodenum by a gallstone

Bouveret's syndrome

446

Acid-base abnormality associated with renal tubular acidosis

Non-anion gap metabolic acidosis

447

Diagnosis for urine finding under polarized light

Fat droplet, lipiduria, or nephrotic syndrome (accept any)
[google photo]

448

Cause of renal insufficiency and sterile pyuria associated with prior antibiotic treatment

Acute interstitial nephritis

449

Type of stones treated by alkalinization of the urine

Uric acid stones

450

Renal syndrome associated with venous thromboembolism

Nephrotic syndrome

451

Hematologic paraneoplastic syndrome associated with renal cancer

Polycythemia

452

Most common of all paraneoplastic syndromes

Hypercalcemia

453

Diagnosis for perioral pigment spots and polyps of small bowel, colon, and stomach

Peutz-Jeghers syndrome

454

The fastest increasing cancer in the U.S.

Thyroid cancer

455

Most common syndrome of inherited renal cancer

von Hippel-Lindau disease

456

Anticonvulsant drug most commonly associated with gum hypertrophy

Phenytoin (accept Dilantin)

457

Syndrome characterized by tinnitus, hearing loss, vertigo, and aural fullness

Meniere's disease

458

Diagnosis for velvety red, premalignant oral lesion

Erythroplakia

459

Bacterial syndrome associated with external otitis and facial nerve paralysis

Malignant external otitis

460

Name of therapeutic maneuver for benign positional vertigo

Epley otolith repositioning maneuver

461

Word describes a yellow discoloration of cerebrospinal fluid

Xanthochromia

462

Eponym associated with impaired memory, ophthalmoparesis, and ataxia

Wernicke's disease

463

Dementing disease associated with parkinsonism and hallucinations

Dementia with Lewy bodies

464

Eponym for viral syndrome causing unilateral vesicles, facial paralysis, and auditory or vestibular symptoms

Ramsay Hunt syndrome (accept herpes zoster oticus)

465

Second most common entrapment neuropathy of the upper extremity

Cubital tunnel syndrome

466

Diagnosis for recurring thoughts causing anxiety and repetitive physical behaviors

Obsessive-compulsive disorder

467

Diagnosis for panic attacks resulting from being reminded of trauma

Posttraumatic stress disorder

468

Diagnosis for diffuse worries about bad things that could happen

Generalized anxiety disorder

469

Anxiety specific to the fear of criticism and being embarrassed

Social anxiety disorder (accept social phobia)

470

Anxiety about being in places or situations from which escape might be difficult

Agoraphobia

471

Infection characterized by white plaques on inflamed mucosa that can be removed

Candidiasis

472

Name of sign associated with dislodgement of epidermis with lateral pressure

Nikolsky's sign

473

Disease associated with "corkscrew hairs"

Scurvy

474

Severe hypomagnesemia inhibits this hormone

Parathyroid hormone

475

A device that tests peripheral sensation in diabetes

Monofilament (accept tuning fork)

476

Autoimmune hematologic disease associated with type 1 diabetes

Pernicious anemia

477

Most sensitive hormonal measure of early pituitary dysfunction

Growth hormone

478

Eponym for hyperthyroidism, a multi-nodular goiter, and recent exposure to iodine

Jod-Basedow phenomenon

479

Vector for West Nile virus disease

Mosquitoes

480

Diagnosis suggested by severe sore throat with dyspnea, drooling, and stridor

Epiglottitis

481

Most common cause of liver abscess worldwide

Amebic liver abscess

482

Most common location of Mycobacterium marinum granuloma

Digit (accept hand)

483

Common diagnosis associated with edematous and pale nasal mucosa

Allergic rhinitis

484

First-line topical drug for allergic rhinitis

Intranasal corticosteroids

485

Screening test for hereditary angioedema

C2 and C4 levels, C1-INH [C1 esterase inhibitor] (any acceptable)

486

Most common disease causing inability to produce antibody to specific antigen

Common variable immunodeficiency

487

Acute, non-allergic fever, rash, and hypotension following treatment of primary syphilis

Jarisch-Herxheimer reaction

488

Hematologic complication associated with glycoprotein IIb/IIIa receptor antagonists

Thrombocytopenia (bleeding accepted)

489

Diagnosis for chest pain and ST-segment elevation resolving with vasodilator drugs

Selective aldosterone receptor antagonist that limits ventricular remodeling after MI

490

Selective aldosterone receptor antagonist that limits ventricular remodeling after MI

Eplerenone

491

The major cause of renal artery stenosis in the Indian subcontinent

Takayasu's arteritis

492

Infectious agent associated with anal cancer

Human papillomavirus

493

Traditional culture media for urogenital gonorrhea

Thayer-Martin agar

494

Viral DNA found in primary central nervous system lymphoma

Epstein-Barr virus

495

Diagnosis suggested by hypotension, fever, rose spots, and bradycardia

Typhoid fever

496

Non-blanching finding associated with bleeding

Petechiae

497

Most common cause of generalized pruritis in the elderly

Xerosis (dry skin acceptable)

498

Diagnosis associated with acute tenosynovitis and this skin finding

Disseminated gonorrhea (accept gonorrhea)

499

Underlying vascular cause of chronic skin condition on left leg

Venous insufficiency

500

Primary skin disease associated with rhinophyma

Rosacea

501

Isolated insulin in a Toronto research laboratory

Sir Frederick Banting and Charles Herbert Best (either last name acceptable)

502

Previous name for reactive arthritis

Reiter's syndrome

503

Year in which first cases of Pneumocystis pneumonia reported in homosexual men

1981

504

Discovered vitamin B12

George Minot, William Murphy, or George Whipple (any last name)

505

First to describe the microscopic appearance of pulmonary capillaries

Marcello Malpighi (accept last name)

506

Common poisonous gas that is odorless, colorless, and tasteless

Carbon monoxide

507

Common ingested substance that increases the hepatic toxicity of methotrexate

Alcohol

508

Initial symptoms of Amanita phalloides poisoning

Nausea and vomiting, abdominal pain, diarrhea (accept any)

509

Diagnosis associated with vomiting, diarrhea, and paresthesias within hours of eating fish

Ciguatera fish poisoning

510

Drug for nerve gas exposure that reactivates acetylcholinesterase

Pralidoxime (2-PAM)

511

Most common non-iatrogenic cause of adrenal insufficiency in the United States

Autoimmune adrenalitis (accept Addison's disease)

512

Oral hypoglycemic agent that should discontinued prior to contrast imaging studies

Metformin

513

Diagnosis suggested by high insulin, proinsulin, C-peptide levels and hypoglycemia

Insulinoma

514

Long-acting, irreversible nonselective alpha-blocker used for pheochromocytoma

Phenoxybenzamine

515

Drug stimulates new bone formation by increasing osteoblast activity

Teriparatide (accept recombinant human parathyroid hormone)

516

The first sign of bladder cancer

Hematuria

517

Condition associated with dysmorphic red blood cells in the urine

Glomerulonephritis

518

Nutrient malabsorption causing hyperoxaluria

Fat

519

Renal vascular disease associated with angiographic "string of beads" appearance

Fibromuscular disease (accept fibromuscular dysplasia)

520

Diagnosis for absence of all cerebral hemispheric and brainstem functions

Brain death (accept dead or death)

521

Disease associated with Kayser-Fleischer rings

Wilson's disease (accept hepatolenticular degeneration)

522

Most consistently effective treatment for spasmodic torticollis (cervical dystonia)

Botulinum toxin injection

523

Diagnosis associated with acute onset of headache, vomiting, and ataxia

Cerebellar infarction or hemorrhage (accept either)

524

Diagnosis for extra-axial, calcified brain mass with overlying skull hyperostosis

Meningioma

525

Term describing change in size and shape of the ventricle following an MI

Ventricular remodeling (accept remodeling)

526

ECG manifestation of hypocalcemia

Prolonged QT interval

527

First-line drug to prevent recurrent pericarditis

Colchicine

528

Most common type of paroxysmal reentrant supraventricular tachycardia

Atrioventricular nodal reentrant tachycardia

529

City associated with Legionnaire's disease (pneumonia)

Philadelphia

530

Invented the electrocardiogram

Willem Einthoven (accept last name)

531

Vaccine used for over 200 years

Vaccinia virus (accept smallpox vaccine)

532

Discovered tubercle bacillus

Robert Koch (accept last name)

533

Eponym for costochondral swelling and pain

Tietze's syndrome

534

Disease associated with lupus pernio

Sarcoidosis

535

Country with last case of naturally occurring small pox

Somalia

536

Eponym for neck pain with extension of the knee when hip is flexed

Kernig sign

537

Diagnosis for midline cystic mass at level of hyoid bone

Thyroglossal duct cyst

538

Finding described by the medical term lagophthalmos

Inability to close eyes completely

539

Life-saving drug for anaphylactic shock

Epinephrine

540

Most common cause of food-related anaphylaxis

Peanut ingestion (accept nut ingestion)

541

Rhinitis caused by overuse of topical nasal decongestants

Rhinitis medicamentosa

542

Gene responsible for hereditary angioedema

C1-esterase inhibitor gene

543

Immunoglobulin finding in Job's syndrome

Elevated IgE levels

544

Most common anemia associated with variation in erythrocyte distribution width

Iron deficiency

545

Red cell morphology seen on this peripheral blood smear

Spherocytes [look up photo]

546

Irradiated blood reduces the risk of this immune condition

Graft-versus-host disease

547

The anemia associated with koilonychia

Iron deficiency

548

Drug class that inhibits sodium reabsorption in the distal convoluted tubule

Thiazide Diuretic

549

Hepatic complication of erythromycin estolate

Cholestatic hepatitis (accept hepatitis or jaundice)

550

Class of drug associated with Achilles tendon rupture

Fluoroquinolone (accept quinolone)

551

Original source of hirudin

Leeches

552

Emetic drug approved for treating hypomotility ("off") episodes in Parkinson's disease

Apomorphine (accept Apokyn)