Acute & Chronic pancreatitis, Celiac Flashcards Preview

Pharm II Exam 4 > Acute & Chronic pancreatitis, Celiac > Flashcards

Flashcards in Acute & Chronic pancreatitis, Celiac Deck (13)
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1
Q

key concepts for tx of acute pancreatitis

A
  • requires early and aggressive IV fluid resuscitation

- managed similarly to pts w/ sepsis

2
Q

acute discontinuation of what meds can cause pancreatitis?

A

meds for diabetes or hyperlipidemia

3
Q

Do you give prophylactic abx to a pt with acute pancreatitis?

A

no!

4
Q

what do you give to pts with ascending cholangitis or necrotizing pancreatitis?

A

-beta lactam/beta lactase inhibitor (pipercillin/tazobactam)

5
Q

hallmark complications of chronic pancreatitis

A
  • chronic pain
  • malabsorption w/ resultant steatorrhea
  • DM
  • risk of pancreatic CA
6
Q

what are the primary treatments for malabsorption due to chronic pancreatitis?(2)

A
  • pancreatic enzyme supplementation (enteric-coated pancreatic enzyme)
  • reduction in dietary fat intake
7
Q

Addition of what may increase the effectiveness of enzyme therapy for malabsorption in chronic pancreatitis?

A

addition of an antisecretory agent to pancreatic enzyme supplementation

8
Q

when do pts take pancreatic enzyme supplementation?

A

during or just after meals

9
Q

How do pancreatic enzymes help to treat pain a/w pancreatitis?

A

they help break down CCK (which increases pancreatic secretion)

Normally CCK is inhibited by trypsin but pts w/ chronic pancreatitis have decreased trypsin. So pancreatic enzyme supplements assist with breaking down the CCK

10
Q

what needs to be considered when treating a patient with Celiac dz?

A

things often overlooked as sources of gluten:

  • oral prescription drugs
  • nonprescription drugs
  • vitamin and mineral supplements
11
Q

Pancreatic enzyme supplementation is dosed based on what?

A

lipase

12
Q

What analgesic is commonly used first line in chronic pancreatitis?

A

Tramadol

13
Q

What is celiac disease a/w?

A

Hyposplenism