Acute Interstitial Nephritis Flashcards
1
Q
What drugs commonly cause acute interstitial nephritis?
A
Abx most common:
penicillin
rifampicin
Others:
NSAIDs
allopurinol
furosemide
2
Q
What systemic diseases can cause acute interstitial nephritis?
A
SLE
sacroidosis
Sjogrens
3
Q
What infections can cause acute interstitial nephritis?
A
Hanta virus
staphylococci
4
Q
Describe AIN on histology
A
- marked interstitial oedema
- interstitial infiltrate in the connective tissue between renal tubules
5
Q
Clinical features of AIN
A
Fever
rash
arthralgia
eosinophilia
mild renal impairment
hypertension
6
Q
What investigations can be used to help diagnose AIN?
A
sterile pyuria
white cell casts
7
Q
Which condition(s) does the following describe:
Young female with fever, weight loss and painful, red eyes.
Urinalysis is positive for leukocytes and protein.
A
Tubulointerstitial nephritis with uveitis
8
Q
A
