Acute Lymphoblastic Leukemia

Question 1

Neoplastic accumulation of lymphoblasts in the bone marrow ?

Answer 1

ALL

Question 2

Lymphoblasts are positive nuclear stain by ?

Answer 2

TdT

DNA polymerase

Question 3

TdT absent where ?

Answer 3

1. Myeloid blast
2. Mature lymphocytes

Question 3

Classifaction of ALL ?

Answer 3

1. B-ALL
2. T-ALL

Question 4

B-ALL express which surface marker ?

B-ALL = Most common

Answer 4

1. CD10
2. CD19
3. CD20

TdT +

Question 4

Common occurance of ALL ?

Answer 4

1. Children
2. Down syndrome

Question 5

Chemotherapy response excellent ?

Answer 5

B-ALL

Question 6

B-ALL requires prophylaxis where ?

Answer 6

1. Scrotum
2. CSF

Question 7

Prognosis of B-ALL ?

Answer 7

1. t (12-21) = Good = Children
2. t ( 9-22) = Poor = Adult

Question 8

t (9-22) name ?

Answer 8

Philadelphia ALL

Question 9

TALL doesnot express which marker ?

Answer 9

CD10

Question 9

T-cell ALL WHich ,markers ?

Answer 9

1. CD2
2. CD3
3. CD4
4. CD5
5. CD6
6. CD7
7. CD8

2-8

Question 10

TALL presents in —

Answer 10

Teenagers

Question 11

In which form ?

Answer 11

Mediastinal Thy,ic mass-A L Lymphoma cause the malignant cells form a mass

Pathoma-56