Acute poisoning Flashcards Preview

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Flashcards in Acute poisoning Deck (26):
1

3 timeframes of poison exposure

1. acute
2. chronic
3. acute on chronic

2

top 3 products

1. pain meds
2. sleeping pills
3. household products

3

treatment steps for poisoned PT

1. remove from harm
2. ABCs
3. treat PT, not poisoning
4. minimize absorption
5. enhance elim
6. use antagonism or antidote if possible

4

action of charcoal

help adsorb the product

5

where is charcoal not used (3)

1. low molecular weights (alcohols)
2. metals, highly ionized salts
3. Pt has unprotected airways

6

ratio of charcoal

10:1

7

when to induce vomiting

not usually done anymore - maybe if right after

8

when to lavage

only if very toxic substance has recently been taken (<1hour)

9

when to use whole bowel irrigation

metals or enteric coated drugs

10

how can metabolism be targeted

for agent that need to be bioactivated (glycol) to toxic species, slow the metabolism

11

2 ways to enhance elimination

1. bicarb to elim acidic species
2. hemodyalisis

12

N-acetycysteine fixes

- thiol donor

13

naloxone fixes

opiods

14

calcium fixes

CCBs

15

glucagon fixes

B-blockers, CCBs

16

fomepizole fixes

ADH

17

digoxin fabs

digoxin toxicity

18

deferoxamine fixes

iron OD

19

atropine fixes

anti-muscarinic

20

what is anion gap formula and when to tell

Na - Cl- bicarb (>12)

21

what is osmolar gap formula and when to tell

OSM - 2xNa - BUN - gluc

22

5 causes of elevated OSM gap

ME DIE
Methanol
Ethylene glycol
Diuretics (mannitol)
Isopropyl alc
Ethanol

23

what is para symp toxidrome

DUMBBELS
Diarrhea
Urination
Miosis, muscle weakness
Bronchospasm
Bradycardia
Emesis
Lacrimation
Salivation

24

Muscarinic toxidrome

SLUDGE
Salivation
Lacrimation
Urination
Diarrhea
GI upset
Emesis

25

Nicotinic toxidrome

Muscle fasciculations
Cramping
Hypertension
Tachycard
Pupil dilation
Pallor

26

Anticholinergic mneumonic

mad as a hatter
dry as a bone
red as a beet
hot as a hare
blind as a bat

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