Adenosine Triphosphate (ATP)

Question 1

A 70kg person uses about _____kg of ATP during a restful day

Answer 1

40kg

Question 2

How long is the life cycle of ATP

Answer 2

seconds to minutes - very short

Question 3

What are the high energy bonds formed between phosphates in ATP

Answer 3

phosphoanhydride bonds

Question 4

What is deltaG for the hydrolysis of ATP

Answer 4

about -50 kJ/mol
*the negative symbolizes energy release

Question 5

How many high energy bonds are present in ATP

Answer 5

2 (2 bonds between 3 phosphates)

Question 6

Hydrolysis of the link between gamma and beta phosphate yields ADP and Pi, releasing ___________kJ of energy

Answer 6

30 kJ

Question 7

Hydrolysis of the link between beta and alpha phosphates yield _______ and _______

Answer 7

AMP and PPi

Question 8

PPi is immediately hydrolyzed in the cell by the enzyme ________________ to give 2 moles of Pi

Answer 8

pyrophosphatase

Question 9

The free energy of hydrolysis of ATP to AMP + PPi is ___________________ as the free energy of hydrolysis of ATP to ADP + Pi

Answer 9

twice as large

Question 10

What is the difference between synthases and synthetases

Answer 10

they are both synthesizing enzymes, however synthases function without the need of ATP whereas synthetases require the use of ATP

Question 11

ATP provides energy not by simple hydrolysis but by

Answer 11

group transfer

Question 12

What is the difference between endergonic and exergonic reactions

Answer 12

exergonic produce products with less free energy than reactants, endergonic produce products with more free energy than reactants

Question 13

What are three reasons behind the large and negative delta G associated with the hydrolysis of ATP

Answer 13

1. hydrolysis releases electrostatic repulsion
2. the product inorganic phosphate has greater resonance stabilization than ATP
3. the ADP2- product rapidly ionizes to release a proton into a medium of very low [H+] driving the hydrolysis towards completion