Adrenal Hormones Flashcards Preview

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Flashcards in Adrenal Hormones Deck (28):
1

betamethasone

corticosteroid

2

cortisone

corticosteroid

3

dexamethasone

corticosteroid

4

fludrocortisone

corticosteroid

5

hydrocortisone

corticosteroid

6

methylprednisolone

corticosteroid

7

prednisolone

corticosteroid

8

prednisone

corticosteroid

9

triamcinolone

corticosteroid

10

eplenerone

inhibitor of adrenocorticoid biosynthesis

11

ketoconazole

inhibitor of adrenocorticoid biosynthesis

12

spironolactone

inhibitor of adrenocorticoid biosynthesis

13

these drugs bind to specific ic cytoplasmic receptors ; the receptor hormone complex regulates gene transcription

adrenocorticosteroids

14

what Is the most important property for glucocorticoids

anti-inflammatory ( these drugs also cause increase in IOP)

15

this drug is given to correct Addisons Disease ( primary, secondary, and tertiary)

hydrocortisone ( fludrocortisone may also be required)

16

which drug is used as a suppression test for Cushings Syndrome

dexamethasone

17

this disease is caused by adrenal cortex dysfunction

Addison disease ( primary adrenocortical insufficiency)

18

this syndrome is caused by hypersecretion of glucocorticoids

cushing syndrome

19

this results from enzyme defect in the synthesis of adrenal hormones

congenital adrenal hyperplasia

20

which drug is a regulator of lung maturation

fetal cortisol ( bexamethasone or dexamethasone)

21

which steroid is preferred in pregnancy

prednisone ( minimizes effect on the fetus)

22

adverse effects of these drugs include increased IOP, decreased growth in kids, glaucoma, centripetal dist. of fat, osteoporosis, increased risk of infection, and hirsutism( increased hair growth), increased appetite, emotional disturbances, peptic ulcer, hypertension, peripheral edema, and hypokalemia

adrenal corticosteroids

23

this drug is an inhibitor of adrenocorticosteroid biosynthesis and function; it strongly inhibits all gonadal and adrenal steroid hormone synthesis; its also an antifungal and is used to treat Cushing Syndrome

ketoconazole

24

this drug is an inhibitor of adrenocorticosteroid biosynthesis and function; it is an antihypertensive that competes for mineralocorticoid receptor

spironolactone

25

this drug is an inhibitor of adrenocorticosteroid biosynthesis and function; this drug binds to the mineralocorticoid receptor ; aldosterone antagonist

eplenerone

26

when do you avoid steroids in OD office

herpes simples epithelial keratitis, bacterial or fungal infection, and large corneal epithelial defects

27

what is the most common oral steroid in an OD office; used for severe uveitis or for skin reactions around eyes/face

Medrol Dosepak ( methylprednisolone)

28

these drugs are useful in the tx of asthma, allergic rhinitis, and allergic reactions

adrenal corticosteroids