Adrenal Hormones Flashcards Preview

Pharmacology II > Adrenal Hormones > Flashcards

Flashcards in Adrenal Hormones Deck (28)
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1
Q

betamethasone

A

corticosteroid

2
Q

cortisone

A

corticosteroid

3
Q

dexamethasone

A

corticosteroid

4
Q

fludrocortisone

A

corticosteroid

5
Q

hydrocortisone

A

corticosteroid

6
Q

methylprednisolone

A

corticosteroid

7
Q

prednisolone

A

corticosteroid

8
Q

prednisone

A

corticosteroid

9
Q

triamcinolone

A

corticosteroid

10
Q

eplenerone

A

inhibitor of adrenocorticoid biosynthesis

11
Q

ketoconazole

A

inhibitor of adrenocorticoid biosynthesis

12
Q

spironolactone

A

inhibitor of adrenocorticoid biosynthesis

13
Q

these drugs bind to specific ic cytoplasmic receptors ; the receptor hormone complex regulates gene transcription

A

adrenocorticosteroids

14
Q

what Is the most important property for glucocorticoids

A

anti-inflammatory ( these drugs also cause increase in IOP)

15
Q

this drug is given to correct Addisons Disease ( primary, secondary, and tertiary)

A

hydrocortisone ( fludrocortisone may also be required)

16
Q

which drug is used as a suppression test for Cushings Syndrome

A

dexamethasone

17
Q

this disease is caused by adrenal cortex dysfunction

A

Addison disease ( primary adrenocortical insufficiency)

18
Q

this syndrome is caused by hypersecretion of glucocorticoids

A

cushing syndrome

19
Q

this results from enzyme defect in the synthesis of adrenal hormones

A

congenital adrenal hyperplasia

20
Q

which drug is a regulator of lung maturation

A

fetal cortisol ( bexamethasone or dexamethasone)

21
Q

which steroid is preferred in pregnancy

A

prednisone ( minimizes effect on the fetus)

22
Q

adverse effects of these drugs include increased IOP, decreased growth in kids, glaucoma, centripetal dist. of fat, osteoporosis, increased risk of infection, and hirsutism( increased hair growth), increased appetite, emotional disturbances, peptic ulcer, hypertension, peripheral edema, and hypokalemia

A

adrenal corticosteroids

23
Q

this drug is an inhibitor of adrenocorticosteroid biosynthesis and function; it strongly inhibits all gonadal and adrenal steroid hormone synthesis; its also an antifungal and is used to treat Cushing Syndrome

A

ketoconazole

24
Q

this drug is an inhibitor of adrenocorticosteroid biosynthesis and function; it is an antihypertensive that competes for mineralocorticoid receptor

A

spironolactone

25
Q

this drug is an inhibitor of adrenocorticosteroid biosynthesis and function; this drug binds to the mineralocorticoid receptor ; aldosterone antagonist

A

eplenerone

26
Q

when do you avoid steroids in OD office

A

herpes simples epithelial keratitis, bacterial or fungal infection, and large corneal epithelial defects

27
Q

what is the most common oral steroid in an OD office; used for severe uveitis or for skin reactions around eyes/face

A

Medrol Dosepak ( methylprednisolone)

28
Q

these drugs are useful in the tx of asthma, allergic rhinitis, and allergic reactions

A

adrenal corticosteroids