Adrenoceptor Blockers Flashcards Preview

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Flashcards in Adrenoceptor Blockers Deck (3):
1

Irreversibly blocks alpha receptors.
Used for pheochromocytoma (pre-surgical)

Phenoxybenzamine

2

Reversible blocks alpha receptors.
Used to treat rebound hypertension and pheochromocytoma (pre-surgical).
Antidote to alpha-1 agonist overdose

Phentolamine, tolazoline

3

Alpha-1 blocker used for BPH and hypertension. Side effects include first dose orthostatic hypotension and reflex tachycardia.

Prazosin
SimD: Tamsulosin (most selective for prostatic smooth muscle), doxazosin, terazosin, silodosin, alfuzosin

NOTE: Alpha-1 selectivity has the pharmacologic advantage of less common and less severe reflex tachycardia.

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