AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - Drugs of abuse Flashcards Preview

Pharmacology > AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - Drugs of abuse > Flashcards

Flashcards in AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - Drugs of abuse Deck (34):
1

Psychologic dependence is

Compulsive drug-seeking behavior

2

Tolerance is associated with

- An ability to compensate for the drug effect
- Increased disposition of the drug after chronic use
- Compensatory changes in receptors, effector enzymes, or membrane actions of the drug

3

Addiction is associated with the existence of

- Psychological dependence
- Physiological dependence
- Tolerance

4

Substances causing narco- and glue sniffings are

- Stimulants
- Psychedelics
- Sedative drugs

5

Substances causing narco- and glue sniffings are not

Antipsychotic drugs

6

Which abused drugs do not belong to sedative agents?

Cannabinoids

7

Psychedelics are

- LSD
- Marijuana
- Volatile substances (glues, solvents, volatile nitrites and nitrous oxide)

8

Psychedelics are not

Cocaine

9

In contrast to morphine, heroin is

More addictive and fast-acting

10

True or False. Symptoms of opioid withdrawal begin 8-10 hours after the last dose.

TRUE

11

The acute course of opioid withdrawal may last

7-10 days

12

Indicate the sedative-hypnotic agent, which has the highest abuse potential

Phenobarbital

13

Characteristics of barbiturate intoxication (2-3 dose) include

- Pleasant feelings of the “blow” in the head, vertigo, myasthenia, stupor
- Locomotive, speech excitation, sharp swings from a cheerful mood to an aggressive state
- Sleep with the subsequent weakness and headaches

14

Characteristics of barbiturate intoxication (2-3 dose) do not include

Perceptual distortion of surroundings, disorders of thinking, behavior

15

Barbiturate abstinent syndrome is shown by

- Crisis by 3 day of abstention
- Anxiety, mydriasis, myasthenia, muscular convulsions, vomiting, diarrhea
- Psychosis as delirium (color visual and auditory hallucinations)

16

Which tranquilizers belongs to strong euphorizing agents?

Diazepam

17

Tranquilizers intoxication (5-10 tablets) features include:

Euphoria, burst of energy, increase in motor activity, wave warmth all over the body

18

Which abused drugs is related to stimulants?

- Cocaine
- Amphetamine
- Caffeine

19

Cocaine exerts its central action by

Inhibiting dopamine and norepinephrine reuptake

20

“Crack” is a derivative of

Cocaine

21

Cocaine intoxication appears by

- Short clouding of consciousness, lightness of body and a feeling of flight
- Wave warmth all over the body, physical bliss, motionlessness
- Clear consciousness, improved mood, influx of physical and spiritual forces, locomotive and speech excitation,
reappraisal of personality

22

Which stimulants is related to psychedelics?

“ecstasy” (methylenedioxymethamphetamine)

23

Cocaine may cause

- Powerful vasoconstrictive reactions resulting in myocardial infarctions
- The multiple brain perfusion defects
- Spontaneous abortion during pregnancy

24

Characteristics of cocaine abstinent syndrome include

- Feeling of depression, irritability, confusion, insomnia (the first 3 days)
- Depression, apathy, excessive appetite, a wish to sleep (the subsequent 1-2 days)
- New attack of depression, anxiety, irritability, dullness, intense thirst for cocaine (after 1-5 days improvement)

25

Characteristics of cocaine abstinent syndrome do not include

Psychosis as color visual and auditory hallucinations (for 3 day)

26

Overdoses of cocaine are usually rapidly fatal from

- Respiratory depression
- Arrhythmias
- Seizures

27

Which agents is related to hallucinogens?

LSD

28

LSD produces

- Mood swings
- Impaired memory, difficulty in thinking, poor judgment
- Perceptual distortion

29

LSD decreases in brain

5-HT2 receptor densities

30

Which agents is related to cannabis?

Hashish

31

The early stage of cannabis intoxication is characterized by

- Euphoria, uncontrolled laugher
- Alteration of time sense, depersonalization
- Sharpened vision

32

Which physiologic signs is a characteristic of cannabis intoxication?

Reddening of the conjunctiva

33

Industrial solvent inhalation causes

- Quick intoxication, lasting only 5-15 minutes
- Euphoria, relaxed “drunk” feeling
- Disorientation, slow passage of time and possible hallucinations

34

Indicate the drugs of choice for reversing the withdrawal syndrome

- Benzodiazepines
- Neuroleptics
- Antidepressants

Decks in Pharmacology Class (41):