AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - General anesthetics Flashcards Preview

Pharmacology > AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - General anesthetics > Flashcards

Flashcards in AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM - General anesthetics Deck (31):
1

The state of “general anesthesia” usually includes

- Analgesia
- Loss of consciousness, inhibition of sensory and autonomic reflexes
- Amnesia

2

Inhaled anesthetics and intravenous agents having general anesthetic properties

Directly activate GABAA receptors

3

Indicate the anesthetic, which is an inhibitor of NMDA glutamate receptors:

Ketamine

4

An ideal anesthetic drug would

- Induces anesthesia smoothly and rapidly and secure rapid recovery
- Posses a wide margin of safety
- Be devoid of adverse effects

5

Which general anesthetics belongs to inhalants?

Desfluran

6

Indicate the anesthetic, which is used intravenously

Propofol

7

Which inhalants is a gas anesthetic?

Nitrous oxide

8

Sevoflurane has largely replaced halothane and isoflurane as an inhalation anesthetic of choice because

- Induction of anesthesia is achieved more rapidly and smoothly
- Recovery is more rapid
- It has low post- anesthetic organ toxicity

9

The limitation of sevoflurane is

Chemically unstable

10

Which inhalants lacks sufficient potency to produce surgical anesthesia by itself and therefore is commonly used with another inhaled or intravenous anesthetic?

Nitrous oxide

11

Which inhaled anesthetics has rapid onset and recovery?

- Nitrous oxide
- Desflurane
- Sevoflurane

12

Indicate the inhaled anesthetic, which reduces arterial pressure and heart rate

Halothane

13

Which inhaled anesthetics causes centrally mediated sympathetic activation leading to a rise in blood pressure and heart rate?

Desflurane

14

Indicated the inhaled anesthetic, which decreases the ventilatory response to hypoxia

Nitrous oxide

15

Which inhaled anesthetics is an induction agent of choice in patient with airway problems?

Halothane

16

Indicate the inhaled anesthetic, which causes the airway irritation

Desflurane

17

Which inhaled anesthetics increases cerebral blood flow least of all?

Nitrous oxide

18

Indicate the inhaled anesthetic, which should be avoided in patients with a history of seizure disorders

Enflurane

19

Which inhaled anesthetics can produce hepatic necrosis?

Halothane

20

Indicated the inhaled anesthetic, which may cause nephrotoxicity

Soveflurane

21

Which inhaled anesthetics decreases metheonine synthase activity and causes megaloblastic anemia?

Nitrous oxide

22

Unlike inhaled anesthetics, intravenous agents such as thiopental, etomidate, and propofol

- Have a faster onset and rate of recovery
- Provide a state of conscious sedation
- Are commonly used for induction of anesthesia

23

Indicate the intravenous anesthetic, which is an ultra-short-acting barbiturate

Thiopental

24

Indicate the intravenous anesthetic, which is a benzodiazepine derivative

Midazolam

25

Which agents is used to accelerate recovery from the sedative actions of intravenous benzodiazepines?

Flumazenil

26

Neuroleptanalgesia has the following properties

- Droperidol and fentanyl are commonly used
- It can be used with nitrous oxide to provide neuroleptanesthesia
- Confusion and mental depression can occur as adverse effects

27

Neuroleptanalgesia has not the following properties

Hypertension is a common consequence

28

Which intravenous anesthetics has antiemetic actions?

Propofol

29

Indicate the intravenous anesthetic, which causes minimal cardiovascular and respiratory depressant effects

Etomidate

30

Indicate the intravenous anesthetic, which produces dissociative anesthesia

Ketamine

31

Ketamine anesthesia is associated with

- Cardiovascular stimulation
- Increased cerebral blood flow, oxygen consumption and intracranial pressure
- Disorientation, sensory and perceptual illusions, and vivid dreams following anesthesia

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