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Flashcards in Airway disease Deck (14):
1

Bronchiectasis:
What disease are seen on the upper lobe?

CF
Allergic bronchopulmonary aspergillosis
Primary ciliary dyskinesia
Autoimmune/connective tissue causes;

2

Bronchiectasis:
What disease are seen on the middle lobe?

NonTB mycobaterial infection;
MAC infection

3

Bronchiectasis:
What disease are seen on the lower lobe?

Chronic recurrent aspiration
End-stage fibrotic disease
Recurrent infections associated with immunodeficiency

4

Bronchiectasis:
What is the Dx test?

HRCT

5

Bronchiectasis:
Do you treat with routine use of short acting or long acting bronchodilators?

NO

6

Bronchiectasis:
DO you treat with long term steroids?

NO

7

Bronchiectasis:
What is used to reduce viscosity of sputum in CF patients?

Dornase alfa

8

Cystic fibrosis
How is it inherited?

Autosomal recessive

9

Cystic fibrosis
What gene is mutated?

CF transmembrane conductance regulator (CFTR) gene

10

Cystic fibrosis
Dx

1. Clinical presentations
2. Biochemical
3. Genetic test for CFTR mutation

11

Cystic fibrosis
What are the biochemical test?

1. Sweat testing
2. Nasal potential difference

12

Cystic fibrosis
Rx

1. Airway clearance
2. Antibx therapy
3. Nutritional support
4. Psychosocial support

13

Cystic fibrosis
What are other clinical findings?

Recurrent pancreatitis;
Male infertility
Chronic sinusitis
Severe nasal polypsis
Non TB mycobaterial infection
Allergic bronchopulmonary aspergillosis
Bronchiectasis
Positive sputum culture for Burkholderia cepacia

14

Cystic fibrosis
What is the most specific infection?

Burkholderia cepacia