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Pharmacology > Alcohols > Flashcards

Alcohols Flashcards

1
Q

Antidote in methanol and ethylene glycol poisoning

A

Ethanol

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2
Q

Methanol causes increase level of

A

FORMIC ACID (formate)

visual disturbances (RETINAL DAMAGE and BLINDNESS), coma, seizures, acidosis, death

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3
Q

Ethylene glycol (antifreeze) causes increase level of

A

toxic aldehydes and OXALIC ACID (oxalate)

KIDNEY DAMAGE and SEVERE ACIDOSIS

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4
Q

Drugs used in ACUTE alcohol withdrawal

A

Diazepam

Thiamine (Vitamin B1)

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5
Q

Given to patients suspected of ALCOHOL DEPENDENCE to prevent Wernicke-Korsakoff Syndrome

A

Thiamine (Vitamin B1)

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6
Q

Drugs used in CHRONIC ALCOHOLISM

A

Naltrexone
Acamprosate
Disulfiram

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7
Q

MOA of NALTREXONE

A

nonselective competitive antagonist of opioid receptors

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8
Q

MOA of DISULFIRAM

A

inhibits ALDEHYDE DEHYDROGENASE

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9
Q

Drugs used in ACUTE METHANOL or ETHYLENE GLYCOL TOXICITY

A

FOMEPIZOLE

(-) ALCOHOL DEHYDROGENASE

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Pharmacology (72 decks)

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