Amino Acids

Question 1

Which Amino acids are target of protein kinase C and protein kinase A

Answer 1

Serine
Threonine

Question 2

Which amino acid is precursor of Serotonin and Niacin

Answer 2

Tryptophan

Question 3

Methyl Xanthines are inhibitors of which enzyme

Answer 3

Phosphodiesterase (converts cAMP to 5’ AMP)

Question 4

Ketogenic Amino acids

Answer 4

Leucine and Lysine

Question 5

Homocystinuria defective enzyme

Answer 5

Cystathionine synthase

Question 6

Fate of Glutamate

Answer 6

Undergoes Oxidative Deamination into Ammonia in liver

Question 7

Amino Acid Involved in Transport of Ammonia from muscles to liver

Answer 7

Alanine

Question 8

High Ammonia
Low Citrulline
High Orotic Acid in urine

Answer 8

Ornithine Transcarbamylase deficiency

Question 9

Urine Turns black on Exposure

Answer 9

Alkaptonuria

Question 10

Alkaptonuria Enzyme defect

Answer 10

Homogentisate Oxidase

Question 11

From which amino acid is Homogentisate derived from

Answer 11

Phenylalanine

Question 12

Homocystinuria Clinical Features

Answer 12

Marfanoid Features + Lens Dislocation

Question 13

Vitamin supplementation for Homocystinuria

Answer 13

B6 (Co-factor for Cystathionine synthase)

Question 14

Urinary Cyanide Nitroprusside test positive in

Answer 14

Cystinuria (Hexagon shaped crystals)

Question 15

Patient developing bruising + pancytopenia after being treated with an antibiotic.

Answer 15

Chloramphenicol (50s ribosome inhibitor)