Amino Acids Flashcards Preview

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Flashcards in Amino Acids Deck (54):
1

which one is the Imino Acid

proline

2

curly hair is abundant in which amino acid

proline

3

pka less then 7 is

acidic

4

pka more then 7 is

basic

5

charged or polar means

soluble

6

uncharges or neutral means

bioavialble

7

losing a H+ means

dissociation

8

which is the amino acid with the closet pka to the body

histidine (6.2)

9

what is caustic (corrosive) ingestion

when you ingest wither a strong acid or a strong base

10

what should you not give to someone after they have ingested a strong acid

syrup of Ipecac (vomiting inducer) because it will burn them again on the way up

11

chronic complication of strong acid/base ingestions

structure formation

12

how to treat myoglobin

bicarb

13

acid used in medicine

ammonia chloride NH4CL

14

base used in medicine

bicarb

15

anode

the positive electrode (where negative particles move towards)

16

cathode

the neg electrode ( where positive particles move towards)

17

what experiment determines pka

titration

18

what is the smallest amino acid with no chiral carbons and is the inhibitory NT of the spinal cord

glycine

19

what are the aromatic (big/bulky) AA's

Phenylalanine
Tyrosine
Tryptophan

20

what are the basic amino acids

leucine and arginine

21

what enzyme recognizes leucine and arginine

trypsin

22

what are the acidic AA's

Aspartic Acid and Glutamic Acid

23

which AA is in the NMDA pathway and helps you geel gooooood

aspartate

24

what blocks the NMDA pathway, therefore blocking ASPARTATE

Glutamate

25

what blocks glutamate and allows the NMDA pathway to function

Memantine

26

what amino acids have sulfur bonds

Cysteine and Methionine

27

what amino acids have N-bonds

Asparagine and Glutamine

28

what amino acids have o binds

Serine
Threonine
Tyrosine

29

what AA is found in the active site of most enzymes

serine

30

what are the branched chain AA

Leucine
Isoleucine
Valine

31

what 4 hormones have a lot of disulfide bonds

insulin
inhibit
GH
prolactin

32

what AA makes catecholamines

tyrosine

33

what AA makes Serotonin

tryptophan

34

what are the ketogenic AA and what does that mean

Leucine
Lysine

means they are made from ACOA and are broken down back into it to make AA's

35

what are the AA's that are both glycogenic and ketogenic

Phenylalanine
isoleucine
threonine
tryptophan

36

name the 10 essential AA's

Phenylalanine
valine
threonine
tryptophan
isoleucine
methionine
histidine
arginine
leucine
lysine

37

methionine makes

cysteine

38

phenylalanine makes

tyrosine

39

inhibitory NT of the brain

GABA

40

order of energy utilization when starving

serum glucose (2-4 hours) -- epinephrine and glucagon
liver glycogen (1.5d)-- epinephrine and glucagon
proteolysis for gluconeoenesis-- Cortisol and GH (prot.) and glucagon
lipolysis -- glucagon
ketogenisis -- glucagon

41

deficient enzyme in PKU

Phenylalanine hydroxyls

42

problem in PKU

unable to make tyrosine so can't make catecholamines or melanin

43

what is the guthrie test and what does it measur

test to see if the child has PKU and it measures the amounts of phenyl acetate and phylpyruvate

44

when should mother with PKU have restricted diet

first 8 weeks while brian is forming

45

what is detected in screening for CAD

17-hydroxylase

46

what is deficient in CAD

21 hydroxylase

47

screening test for celiac sprue

transglutaminase

48

screening test for CF

immunoreactive trypsin

49

deficient in albinism

tyrosinase

50

cause of vitiligo

autoimmune destruction of melanocytes

51

deficient in Alkaptonuria

homogentisic acid oxidase ( increase seen in tyrosine)

52

problem in maple syrup urine disease

build up of branch chain amino acids because the collecting ducts in the kidney cannot transport them

53

defect in Cysteinuria

defect in the renal transport of Cysteine, ornithine, lysine and arginine

54

crystal seen in the urine of someone with cysteinuria

hexagonal/coffin shaped