Amyloidosis

Question 1

Discuss the aetiology and clinical features of the different types of amyloidosis. Discuss the result of a congo red stain for amyloidosis. Discuss the diseases that occur as a result of amyloid build up.(npr)(222)

Answer 1

Amyloid- Classification II(other familial)

• Transthyretin e.g. mutation
• β2 microglobulin – peritoneal dialysis
• Aβ2 protein- Alzheimer’s
• Insulin, calcitonin- endocrine tumours