1
Q
What is sickle cells anaemia
A
deformed less flexible red cells
2
Q
What are complications of red cells
A
- sickle cell crisis
- leg ulcers
- renal failure
- susceptibility to infections
3
Q
What is haemolytic Anaemia
A
breakdown of red cells
4
Q
What should a person take if they have haemolytic anaemia
A
folic acid (increase folate)
5
Q
What medication reduces the chance of painful crisis
A
Hydroxycarbamide
6
Q
How common is G6PD deficiency
A
- common in males
- Asian and African
7
Q
What can a person develop if they have G6PD deficiency
A
Haemolytic anaemia
8
Q
What drugs lead to 100% haemolysis
A
- Floroquinolones
- Nitrofurantoin
- Quinolones
- Dapsone
9
Q
What drugs lead to possible haemolysis
A
- Aspirin
- Quinine
- Sulfonylureas
