Flashcards in Anesthetics Deck (26):
MAC __________ affected by health status, age, drug interactions, and red hair
MAC ________ affected by the type of stimulus, sex, height, weight, or duration of exposure.
Rate of induction influenced by
blood:gas partition coefficient
Conc. of agent is directly proportional to
Induction occurs fastest with agents __________ soluble in blood
Increased cardiac output _____________ rate of induction
_____________ relationship between MAC and lipophilicity
Halothane, halothane and succinylcholine, enflurane, isoflurane, desflurane, sevoflurane
Potent anesthetic. Not repeated at intervals
Metabolism causes liberation of hydrocarbon and bromide ions that can cause hepatitis
Increased risk of malignant hyperthermia. Inability of SR to sequester Ca. Tx is dantrolene
Halothane and succinylcholine
Less potent than halothane. Less sensitization of heart to catecholamines. Respiratory depression is dose dependent. CNS excitation may cause seizures
Structural isomer of enflurane
Dose not induce arrhythmias, sensitize heart to catecholamines, or decrease cardiac output.
Low biotransformation decreases organ toxicity
Newer. Cardiac output maintained. Respiratory depression is dose related
New. Low pungency. Similar to desflurane.
Reacts with soda lime in breathing machine, requires special equipment.
Fluoride released during metabolism, potential for toxicity
Nitrous oxide is halogenated or non-halogenated?
Potent analgesic. Weak anesthetic.
Combined with more potent agents in balanced anesthesia b/c it lowers the threshold of other agents required for anesthesia
Little effect on cardiovascular system. Potentiates circulatory depression of narcotics and opioids
Does not have respiratory depression on its own, but enhances depression of other agents
Can increase volume or pressure within closed body compartments. It replaces ____. Can have occluded middle ear, pneumothorax, gut, and lung
Chronic use of nitrous oxide can cause
A rapidly absorbed gas ______ rate of uptake of a second anesthetic gas. ________ commonly used
Inhalational anesthetics usually eliminated via the