Anesthetics Flashcards Preview

Exam 8 > Anesthetics > Flashcards

Flashcards in Anesthetics Deck (26):
1

MAC __________ affected by health status, age, drug interactions, and red hair

is

2

MAC ________ affected by the type of stimulus, sex, height, weight, or duration of exposure.

is not

3

Rate of induction influenced by

blood:gas partition coefficient

4

Conc. of agent is directly proportional to

partial pressure

5

Induction occurs fastest with agents __________ soluble in blood

less

6

Increased cardiac output _____________ rate of induction

decreases

7

_____________ relationship between MAC and lipophilicity

linear

8

Halothane, halothane and succinylcholine, enflurane, isoflurane, desflurane, sevoflurane

halogenated

9

Potent anesthetic. Not repeated at intervals

Halothane

10

Metabolism causes liberation of hydrocarbon and bromide ions that can cause hepatitis

Halothane

11

Increased risk of malignant hyperthermia. Inability of SR to sequester Ca. Tx is dantrolene

Halothane and succinylcholine

12

Less potent than halothane. Less sensitization of heart to catecholamines. Respiratory depression is dose dependent. CNS excitation may cause seizures

Enflurane

13

Structural isomer of enflurane

Isoflurane

14

Dose not induce arrhythmias, sensitize heart to catecholamines, or decrease cardiac output.
Low biotransformation decreases organ toxicity

Isoflurane

15

Newer. Cardiac output maintained. Respiratory depression is dose related

Desflurane

16

New. Low pungency. Similar to desflurane.

Sevoflurane

17

Reacts with soda lime in breathing machine, requires special equipment.
Fluoride released during metabolism, potential for toxicity

Sevoflurane

18

Nitrous oxide is halogenated or non-halogenated?

Non-halogenated

19

Potent analgesic. Weak anesthetic.
Combined with more potent agents in balanced anesthesia b/c it lowers the threshold of other agents required for anesthesia

Nitrous oxide

20

Little effect on cardiovascular system. Potentiates circulatory depression of narcotics and opioids

nitrous oxide

21

Does not have respiratory depression on its own, but enhances depression of other agents

nitrous oxide

22

Can increase volume or pressure within closed body compartments. It replaces ____. Can have occluded middle ear, pneumothorax, gut, and lung

Nitrous oxide
N2

23

Chronic use of nitrous oxide can cause

megaloblastic anemia

24

A rapidly absorbed gas ______ rate of uptake of a second anesthetic gas. ________ commonly used

increase
Nitrous oxide

25

Inhalational anesthetics usually eliminated via the

lungs

26

Conc. that must be inhaled to produce anesthesia in half of the subjectes

Minimum alveolar conc.
MAC