ANS Drug Effects

Question 1

PNS agonist effect on heart

Answer 1

decrease in heart rate, contractility, and conduction

Question 2

PNS agonist effect on blood vessels

Answer 2

vasodilation

not PNS innervated

Question 3

PNS agonist effect on blood pressure

Answer 3

decreased blood pressure

adverse: hypotension

Question 4

PNS agonist effect on lung

Answer 4

bronchoconstriction

adverse: increased secretions

Question 5

PNS agonist effect on eye

Answer 5

miosis, accomodation (near vision), increased aqueous humor outflow
treats glaucoma

Question 6

PNS agonist effect on GI/GU

Answer 6

increased salivation, detrusor contraction, and motility
treats xerostomia and improves urinary flow
adverse: diarrhea

Question 7

PNS agonist effect on NMJ

Answer 7

muscle contraction

treats myasthenia gravis

Question 8

PNS agonist effect on CNS

Answer 8

memory, cognition, movement

treats alzheimers

Question 9

PNS antagonist effect on heart

Answer 9

increased heart rate

treats bradycardia

Question 10

PNS antagonist effect on blood vessels

Answer 10

no effect; no basal M tone to antagonize

Question 11

PNS antagonist effect on blood pressure

Answer 11

minimal effect

Question 12

PNS antagonist effect on lung

Answer 12

bronchodilation

adverse: increased drying

Question 13

PNS antagonist effect on eye

Answer 13

mydriasis

adverse: blurred vision, decreased outflow, exacerbates glaucoma

Question 14

PNS antagonist effect on GI/GU

Answer 14

decreases salivation, blocks detruser, motility
used to create a dry field, treats overactive bladder and diarrhea
adverse: dry mouth, urinary hesitancy/retention, constipation

Question 15

PNS antagonist effect on NMJ

Answer 15

flaccid paralysis

used in surgery as a muscle relaxer

Question 16

PNS antagonist effect on CNS

Answer 16

treats parkinsons, anti-emetic

adverse: sedation, confusion

Question 17

SNS agonist effect on heart

Answer 17

beta-1: increases heart rate and contractility
treats cardiogenic shock
adverse: pro-arrythmic, precipitates angina

Question 18

SNS agonist effect on blood vessels

Answer 18

alpha-1: vasoconstriction
treats hypotensive shock, decongestant
adverse: hypertension
beta-2: vasodilation

Question 19

SNS agonist effect on blood pressure

Answer 19

alpha-1 and beta-1: increases blood pressure
treats hypotensive shock
beta-2: decreases blood pressure
adverse: hypotension if unopposed by alpha-1

Question 20

SNS agonist effect on lung

Answer 20

beta-2: bronchodilation

treats asthma

Question 21

SNS agonist effect on eye

Answer 21

alpha-1: mydriasis
used during eye exams
betas: increased humor production

Question 22

SNS agonist effect on GI/GU

Answer 22

alpha-2: GI relaxation via decreased ACh release
beta-2,3: smooth muscle relaxation 
treats overactive bladder
alpha-1: close sphincter 
promotes continence 
beta-2: uterine relaxation 
treats premature labor

Question 23

SNS agonist effect on NMJ

Answer 23

beta-2 causes muscle tremors

Question 24

SNS agonist effect on CNS

Answer 24

increases vigilance and focus

treats ADHD

Question 25

SNS antagonist effect on heart

Answer 25

beta-1: decreases heart rate and contractility treats hypertension, angina, arrhythmias, CHF adverse: bradycardia, heart block

Question 26

SNS antagonist effect on blood vessels

Answer 26

alpha-1: vasodilation treats hypertension beta-2 adverse: vasoconstriction, decreased perfusion

Question 27

SNS antagonist effect on blood pressure

Answer 27

alpha-1 and beta-1: decreased blood pressure treats hypertension alpha-2 agonist: decreases blood pressure treats hypertension adverse: dry mouth, sedation

Question 28

SNS antagonist effect on lung

Answer 28

beta-2: bronchospasm

Question 29

SNS antagonist effect on eye

Answer 29

beta-1,2: decreased aqueous humor production, decreased intraocular pressure treats glaucoma

Question 30

SNS antagonist effect on GI/GU

Answer 30

alpha-1: open sphincter | treats micturition disorders and BPH

Question 31

SNS antagonist effect on CNS

Answer 31

betas treat stage fright, essential tremor | adverse: depressed mood, sleep disturbances