Anti-emetics Flashcards
(21 cards)
Which antiemetic is given for post operative nausea?
Metoclopramide and domperidone
Which antiemetic is given for acute gastroenteritis?
Ondansetron, a 5HT3 receptor antagonist
Which antiemetic is given for vestibular disturbances?
HYMS INR hydrobromide, an anti-muscarinic also given for IBS
When should metoclopramide be contraindicated?
Bowel obstruction because it is a 5 HY agonist which increases gut motility
Which antiemetics can worsen Parkinson’s disease symptoms?
Prochlorperazine
Chlorpromazine
-> risk of dystonia reactions
Which antiemetics are Antihistamine H1 antagonists?
Cyclozine, Promethazine hydrochloride
What are the Dopamine antagonists?
Metoclopramide, Domperidone, Prochlorperazine
What are features of metoclopramide?
Max 5 days, don’t give in Parkinson’s and bowel obstruction
What are the features of domperidone?
Doesn’t cross BBB, contraindicated in bowel obstruction and in impaired cardiac conduction
When is prochlorperazine given?
Migraine related N+V
What is given for motion sickness?
Anti muscarine hyoscine hydrobromide prevents motion sickness
What is given for chemo induced nausea and vomiting?
5HT3 receptor antagonist ondansetron
Which antiemetic is licensed treatment for pregnancy?
Metoclopramide, Domperidone, and Ondansetron
Which antiemetics are Antihistamine H1 antagonists?
Cyclozine, Promethazine hydrochloride
What are the Dopamine antagonists?
Metoclopramide, Domperidone, Prochlorperazine
What are features of metoclopramide?
Max 5 days, don’t give in Parkinson’s and bowel obstruction
What are the features of domperidone?
Doesn’t cross BBB, contraindicated in bowel obstruction and in impaired cardiac conduction
When is prochlorperazine given?
Migraine related N+V
What is given for motion sickness?
Anti muscarine hyoscine hydrobromide prevents motion sickness
What is given for chemo induced nausea and vomiting?
5HT3 receptor antagonist ondansetron
Which antiemetic is licensed treatment for pregnancy?
Metoclopramide, Domperidone, and Ondansetron
