Anti-Microbial - General Info Flashcards Preview

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Flashcards in Anti-Microbial - General Info Deck (16):
1

Antimicrobial

Inhibit growth microorganisms

2

Antibacterial

Inhibit growth of bacteria

3

Antibiotic

Inhibits microorganism growth and is made by other microorganisms

4

Bacteriostatic

Reversible growth inhibition
Helps immune system remove it
Don't give to immunocompromomised

5

Bactericidal

Injure/Kill invading microorganism

6

Post-Antibiotic effect

Killing action continues though drug plasma levels undetectable

7

How does the Post-Antibiotic effect occur

Lag time for bacteria to synthesize new products
Persistence of agent at target site
Enhanced susceptibility host defenses

8

Broad Spectrum

Works on several groups

9

Narrow Spectrum

Few groups - Usually DOC

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Extended Spectrum

Gram+ and a few Gram-

11

MBC

Lowest ABX conc to kill 99.9% of colony

12

Empiric Therapy

Immediate therapy required
Don't know what it is

13

Example of Sequential Blockade

TMP + SMX

14

Example of Blockade of Inactivating Enzymes

Clavulanic acid + Amoxicillin

15

Example of Enhanced Drug Uptake

Aminoglycosides after Beta-lactams

16

Resistance

Amount tolerable by host is innefective