Anti-Virals Flashcards Preview

Pharmacology > Anti-Virals > Flashcards

Flashcards in Anti-Virals Deck (11):
0

Enfurvitide

HIV entry inhibitor
Bind to GP 41

1

Maraviroc

HIV entry inhibitors
Blocks CCR5 chemokine receptor found on T cells

2

Zidovudine

HIV replication inhibitor
Nucleoside RT inhibitor
Activated by 3 step phosphorylation

3

Tenofovir

HIV replication inhibitor
Nucleotide RT inhibitor
Fewer phosphorylation steps
Hep B treatment

4

Efavirenz

HIV replication inhibitors
Non-nucleoside RT inhibitors
Not incorporated into viral DNA

5

Raltegravir

HIV integrase inhibitor
Viral integrase inserts viral DNA into host DNA

6

Saquinavir

HIV protease inhibitor
Use with low dose ritonavir reducing it's metabolism ℅ administered as booster
Cleaves Gag precursor protein

7

Ribavirin

Hep C treatment
Nucleoside analogue
Prevents viral RNA synthesis

8

Boceprevir

Hep C treatment
Protease inhibitor

9

Aciclovir

Herpes
Nucleoside analogue

10

Oseltamivir

Influenza
Neuraminidase inhibitor
Prevent virus from exiting host cells