ANTI-VIRALS ⛑

Question 1

Penetration/uncoating

Answer 1

AMANTIDINE

Question 2

Viral DNA polymerase

Answer 2

ACYCLOVIR

FORSCARNET

GANCYCLOVIR

Question 3

Viral RNA polymerase

Answer 3

Foscarnet or Ribavirin

Question 4

Reverse transcriptase

Answer 4

AZT

Question 5

Neuraminidase

Answer 5

Oseltamivir

Question 6

Guanine analog

DOC for CMV retinitis, pneumonia and esophagitis

Answer 6

Gancyclovir

Question 7

Phospahte analog

Answer 7

Foscarnet

Question 8

DOC for CMV retinitis

Answer 8

Foscarnet

Question 9

Anti-virals for Respiratory Viruses

Answer 9

Amantadine

Rimantadine

Ribavirin

Question 10

MOA: inhibit viral uncoating

Used as prophylaxis for Influenza A

PARKINSONISM’S DISEASE

Answer 10

Amantadine and rimantadine

Question 11

For RSV bronchiolitis and pneumonia

Answer 11

Ribavirin

Question 12

Influenza A, B and Lassa fever, Hepatitis C

Answer 12

Ribavirin

Question 13

Two types of Ribavirin:

Reverse transcriptase inhibitors

Protease inhibitors

Answer 13

Ribavirin

Question 14

Thymidine analog

Answer 14

Zidovudine or AZT

Question 15

Adenosine analog

Answer 15

Didanosine or DDL

Question 16

Cytosine analog

Answer 16

Zalcitabine or ddC

Question 17

Thymine analog

Answer 17

Stavudine or d4T

Question 18

Hepa B

Answer 18

Lamivudine

Question 19

Protease inhibitors

Adverse effects: diarrhea, nausea and vomiting

Answer 19

Saquinavir, Ritonavir, Indinavir, Nelfinavir

Question 20

Drugs to prevent infection in HIV

Answer 20

Clarithromycin

Azithromycin

Question 21

> 5mm (TB)

Answer 21

Isoniazid

Rifampicin

Question 22

Drugs for HERPES

Answer 22

Foscarnet

Ganciclovir

Idoxuridine

Vidarabine

Acyclovir

“For herpes, GIV Acyclovir”

Question 23

Most anti metabolites

Pro-drugs

Answer 23

Anti-virals

Question 24

RNA virus REPLICATIVE CYCLE

Answer 24

Hemagglutinin

Uncoating

Replicatiom

Budding or release

Question 25

Transition state analog of sialic acid

Answer 25

Oseltamivir

Question 26

Active against influenza A and B

Answer 26

Oseltamivir

Question 27

MOA: reversible inhibition of viral neuraminidases producing viral aggregation on the cell surface preventing release and spread of viral progeny

Answer 27

Oseltamivir

Question 28

MOA of Oseltamivir involves in bloxking of viral

Answer 28

Release

Question 29

Guanine analog

Answer 29

Acyclovir Ganciclovir

Question 30

For HSV 1 and 2 and Varicella

Answer 30

Acyclovir

Question 31

Adverse effects of Oseltamivir

Answer 31

Crytalluria and neurotoxicity

Question 32

Its not hematotoxic Its nephrotoxic

Answer 32

Acyclovir

Question 33

Acts as a chain terminator

Answer 33

Acyclovir