Antiarryhtmic Flashcards Preview

PHARMA Cardio > Antiarryhtmic > Flashcards

Flashcards in Antiarryhtmic Deck (21):
1

Treatment of all types of arrythmias, WPW syndrome
SE: drug induces lupus

Procainamide

2

SE: Cinchonism (TRIAD)

Quinine, quinide

3

Post MI arrythmias, Digitalis arrythmias
SE: seizures

Lidocaine

4

Contraindicated post-MI, Refractory arrythmias

Flecainide

5

Perioperative and thyrotoxic arrythmias, SVT

Emolol

6

SE: dose dependent torades de pointes

Stoalol

7

Most efficacious antiarrythmic
SE: skin deposits, pulmonary fibrosis, hyper/hypothyroidism

Amiodarone

8

Outpatient management of SVT
SE: gingival hyperplasia

Verapamil

9

What are the effects of class I antiarrythmics on action potential duration?

Class IA: prolongs
Class IB: shortens
Class 1C: No effect

10

Class IA

Quinidine
Procainamide
Disopyramide

11

Class IB

Mexiletine
Tocainide
Lidocaine

BEST post MI

12

What are the drugs that can cause agranulocytosis?

CCCAPPIT
Clozapine
Co-trimoxazole
Colchicine
Aminopyrine
Pheylbutazone
PTU
Indomethacin
Tocainide

13

Class I contraindication

MI

14

Class IC

Propafenone
Flecainide
Encainide

15

Amiodarone toxicity Manifestations

Pulmonary fibrosis
paresthesias
tremors
thyroid dysfunction
corneal deposits
skin deposits

16

why are dihidropyridine calcium channel blckers not useful as antyarrythmics?

DHP CCBs evoke compensatory sympathetic discharge which facilitates arryhtmias rather than terminating them

17

PROLONGS:
PR
QRS
QT intervals

Class 1A
Procainamide

18

Shortens effect on AP duration
No effect on normal cells

Class 1B
Lidocain

19

Prolongs QRS interval
No effect on AP duration

Class 1C
Flecainide

20

Prolongs PR interval
No effect on AP duration

Class 2
Propanolol

Class 4
Verapamil

21

Prolongs QT interval
Prolongs AP duration

Class 3
Dofetilide