Flashcards in Antibacterials 3 Deck (13)
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0
Most broad spectrum so is used for polymicrobial infections
Carbapenems
1
Wide spectrum good activity
Gram neg rods
Gram pos organisms
Anaerobes
Imipinem
2
Imipenem most commonly administered with inhibitor of renal dehydropeptidase
Cilastatin
3
Carbapenem with longest halflife
Ertapenem
4
Carbapenems no effect on
MRSA
E faecium
C difficile
B cepacia
S maltophilia
5
Carbapenems not active against
L monocytogenes
Enterococcus
6
Excessive levels of imipenem in patients with renal failure may lead to
Seizures
7
Carbapenems Cross allergenicity with
Penicillin
8
Beta lactamase inhibitors
Clavulanic acid
Sulbactam
Tazobactam
9
B lactamase inhibitors have their own antibacterial activity, t or f
False
10
Tazobactam especially acts on which B lactamases
SHV-1
TEM
11
Diarrhea
Hepatitis, jaundice
Hemolytic anemia
Tazobactam
12
