Antibacterials 3 Flashcards Preview

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Flashcards in Antibacterials 3 Deck (13)
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0

Most broad spectrum so is used for polymicrobial infections

Carbapenems

1

Wide spectrum good activity
Gram neg rods
Gram pos organisms
Anaerobes

Imipinem

2

Imipenem most commonly administered with inhibitor of renal dehydropeptidase

Cilastatin

3

Carbapenem with longest halflife

Ertapenem

4

Carbapenems no effect on

MRSA
E faecium
C difficile
B cepacia
S maltophilia

5

Carbapenems not active against

L monocytogenes
Enterococcus

6

Excessive levels of imipenem in patients with renal failure may lead to

Seizures

7

Carbapenems Cross allergenicity with

Penicillin

8

Beta lactamase inhibitors

Clavulanic acid
Sulbactam
Tazobactam

9

B lactamase inhibitors have their own antibacterial activity, t or f

False

10

Tazobactam especially acts on which B lactamases

SHV-1
TEM

11

Diarrhea
Hepatitis, jaundice
Hemolytic anemia

Tazobactam

12

Tazobactam used in combination with

Piperacillin