Antibiotic drugs, moa, coverage Flashcards Preview

PT3 ID 1 (HIV) > Antibiotic drugs, moa, coverage > Flashcards

Flashcards in Antibiotic drugs, moa, coverage Deck (40):
1

Penicillin G

IV (no e- withdrawing group)
streptococcus, NEVER staph

2

Penicillin v/k

oral
streptococcus, NEVER staph

3

Oxacillins

oral
staph only

4

nafcillin

staph only

5

ampicillin

gram+
susceptible to beta-lactamase

6

amoxicillin

gram+
susceptible to beta-lactamase

7

ticarcillin

gram-
pseudomonas

8

piperacillin

good gram -/+
pseudomonas
enterococci
anaerobes

9

imipenem/meropenem

some gram+
broad gram-
pseudomonas

10

ertapenem

some gram+
broad gram-
NO pseudomonas, enterococcus, acinetobacter

11

aztreonam

gram-
enterobacteriacea
pseudomonas

12

beta lactam drugs

penicillins
penems
aztreonam
cephalosporins
clavams

13

1st gen cephalosporins

cephalexin
cefazolin
cefadroxil

14

1st gen cephalosporin coverage

broad gram+
no MRSA

15

2nd gen cephalosporins

cefuroxime
cefoxitin
cefproxil

16

2nd gen cephalosporin coverage

broad gram+
some e. coli and klebsiella

17

3rd gen cephalosporins

ceftriaxone
cefixime
cefpodoxime
cefdinir
cefotaxime
ceftazidime

18

3rd gen cephalosporin coverage

some gram+
good for gram- besides pseudomonas

19

3rd gen cephalosporin with pseudomonas coverage

ceftazidime

20

4th gen cephalosporin

cefepime

21

4th gen cephalosporin coverage

some gram+
good gram- including pseudomonas
no anaerobes

22

vancomycin

glycopeptide
great gram+
MRSA
C. diff

23

quinolones

ciprofloxacin
levofloxacin
moxifloxacin

24

quinnolones moa

dna gyrase inhibitor

25

quinolone coverage

good gram-
cipro pseudomonas
moxi anaerobes
levo best gram+

26

trimethoprim moa

inhibits tetrahydrofolic acid production

27

sulfamethoxazole moa

inhibits dihydropteroic acid production

28

tetracyclines moa

ribosome inhibitors at 30s

29

tetracyclines coverage

good gm+
active against MRSA
tigecycline active against VRE/anaerobes

30

macrolides

erythromycin
clarithromycin
azithromycin

31

macrolides moa

ribosome inhibitors at 50s

32

macrolides coverage

streptococcus
some gm-
atypicals

33

side effect of erythromycin

GI cramping

34

side effect of clarithromycin

metallic taste

35

clindamycin moa

ribosome inhibitor at 50s

36

clindamycin coverage

good gm+
anaerobes

37

clindamycin adverse effect

c. diff infection

38

linezolid moa

inhibits ribosome at 50s

39

linezolid coverage

MRSA
VRE

40

linezolid side effects

bone marrow suppression
MAO inhibitor (possible serotonin syndrome)