Flashcards in Antibiotic resistance Deck (10):
What are the 6 main targets of antibiotics?
1-Cell wall synthesis
4-Folic acid (tetrahydrofolate) synthesis)
What are 4 ways bacteria gain resistance to antibiotics?
1-restrict access of antibiotic to target (efflux pumps)
2-Modify the target
3-Enzymatic inactivation or modification of antibiotic
4-Modify expression of bacterial factors needed to activate the antibiotic-prodrugs
How do bacteria become resistant to tetracycline?
altering the 16S rRNA involved in tetracycline binding of the 30S subunit
What drug resistance is an example of multistep process resistance?
How do bacteria develop resistance to aminoglycosides?
modifications that disrupt hydrogen-bonding network used to bind 16S rRNA
A dormant cell that is resistant to many stresses and antibiotic treatments is called?
Which two spore-forming bacteria are persistent in the environment and are common with IV drug users?
C. Tetani, B anthracis
Which spore former causes gas gangrene?
Which 3 spore-formers cause food-borne infections?