Antibiotics

Question 1

Rocky Mountain Spotted Fever

Answer 1

Tetracyclines (doxycycline)

Question 1

Tetracycline suffix

Answer 1

-cycline

Question 2

3 teaching points on tetracyclines

Answer 2

-Take full glass of water, alone
-Photosensitivity
-Can decrease effectiveness of birth control

Question 3

Can tetracyclines be used in pregnancy

Answer 3

No (also stains baby’s teeth)

Question 4

Stepwise approach to acne?

Answer 4

1) OTC (salicylic acid, benzoyl peroxide)
2) prescription benzoyl; tretinoin, erythromycin
3) tetracyclines (minocycline/tetra)

Question 5

Macrolide suffix

Answer 5

-mycin

Question 6

Allergy considerations with macrolides

Answer 6

Good alternative to those allergic to beta-lactams (penicillins, sulfas)

Question 7

What ABX cannot be used with myasthenia gravis

Answer 7

Macrolides (M =/ M)

Question 8

Drug interaction with macrolides

Answer 8

Can increase titer of statins

Question 9

2 major adverse effects of macrolides

Answer 9

Heptatoxicity
QT prolongation

Question 10

Allergy considerations with cephalosporins

Answer 10

Cross sensitivity to penicillins (esp. first generation)

Question 11

MRSA skin infections

Answer 11

Sulfa- trimethoprim-sulfamethoxazole (Bactrim)

Clindamycin

Question 12

Gonorrhea

Answer 12

Cephalosporin- Rocephin IM

Question 13

Impetigo

Answer 13

Cephalosporin- Keflex

Question 14

Pregnant UTI

Answer 14

Cephalosporin- Keflex

Question 15

Strep

Answer 15

Penicillin

Question 16

Otitis media

Answer 16

Penicillin- Amoxicillin

Question 17

Syphilis

Answer 17

Penicillin- Benzathine penicillin

Question 18

3 AE of penicillins

Answer 18

-Diarrhea (sometimes Cdiff)
-Vaginitis
-SJS

Question 19

Contraindication condition for amoxicillin

Answer 19

Mononucleosis (rash)

Question 20

Mastitis

Answer 20

Pencillin– dicloxacillin

Question 21

Fluoroquinolones suffix

Answer 21

-floxacin

Question 22

3 contraindications for fluoroquinolones

Answer 22

Pregnancy
Hx of aortic aneurysm or other risk factors
Myasthenia gravis

Question 23

Traveler’s diarrhea

Answer 23

Fluoroquinolone- Ciprofloxacin

Question 24

Anthrax

Answer 24

Fluoroquinolone- ciprofloxacin

Question 25

Adverse effects of fluoroquinolones

Answer 25

HYPOglycemia QT prolongation Neuropathy Tendinopathy Phototoxicity Do not use <18yo

Question 26

Sulfonamide suffix

Answer 26

-zole

Question 27

Cross sensitivity to sulfas

Answer 27

diuretics

Question 28

G6PD anemia is a contraindication to which abx

Answer 28

Sulfas

Question 29

MRSA Cellulitis

Answer 29

Sulfas- TMP-SMX

Question 30

Bacterial conjunctivitis

Answer 30

Sulfa- sulfacetamide

Question 31

Cross allergy to penicillins

Answer 31

cephalosporins

Question 32

Atypical pneumonia

Answer 32

Macrolide- azithromycin

Question 33

Alternative to penicillins

Answer 33

Macrolides (-mycin)

Question 34

Alternative to macrolides

Answer 34

Tetracycline (doxy) or quinolone

Question 35

Diverticulitis

Answer 35

Augmentin (or cipro/flagyl)