Antibiotics Flashcards Preview

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Flashcards in Antibiotics Deck (17):
1

Penicillins

Disrupt cell wall structures

2

Cephalosporins

Distrupt cell wall synthesis

3

Carapenems

Disrupt cell wall synthesis

4

B-lactamase inhibitors

Disrupt cell wall synthesis

5

Vancomycin

Disrupt cell wall synthesis

6

Bacitracin

Disrupt cell wall synthesis

7

Trimethoprim and sulfamethoxazole

Frolic acid synthesis inhibitors disrupting biosynthesis of nucleic acid precursors

8

Fluoroquinolones
Metronidazole

DNA synthesis inhibitors

9

Rifampin

RNA synthesis transcription inhibitor

10

Macrolides: erythromycin and azithromycin
Aminoglycosides
Tetracyclines
Clindamycin

Protein synthesis inhibitors

11

Penicillins and cephalosporins

Inhibit transpeptidases by binding to penicillin binding proteins

12

Vancomycin

Inhibits transpeptidase

13

Aminoglycosides

Inhibit 30S ribosomal subunit (inhibit protein synthesis)
Blocks initiation complex

14

Tetracyclines

Inhibit protein synthesis through 30s subunit
Blocks binding of aminoacyl-tRN

15

Chloramphenicol, erythmycin, and clindamycin

Inhibits protein synthesis through 50s subunit
Chloramphenicol blocks peptitydl transferase
Erythromycin blocks release of t-RNA

16

Quinolones

Block DNA gyrase

17

Isoniazid

Inhibits synthesis of mycolic acid: treatment for mycobacteria