Antibody & Disease Association Flashcards Preview

Autoantibodies > Antibody & Disease Association > Flashcards

Flashcards in Antibody & Disease Association Deck (24):
1

RF

Rheumatic Disease

2

CCP

RA (Sensitive + Specific)

3

ANA / FANA

SLE (Sensitive), Sjogren, Myositis, Lupus,
Old Age, + FMHx

4

ACH

Sjogren

5

Sc70 / Topo

Diffuse Scleroderma (Specific + Sensitive)

6

Centromere

CREST (Specific + Sensitive)

7

RNA-Poly 3

Scleroderma Renal Crisis

8

Th

Scleroderma PAH

9

PM-Sci

Systemic Scleroderma, Polymyositis

10

PDGF-R

Scleroderma

11

MMP

Scleroderma

12

Histone

Rx-SLE

13

Ro/SSA (ENA)

Sjogren, SLE (Neonatal, SCLE)

14

La/SSB (ENA)

Sjogren, SLE (Neonatal)

15

Sm

SLE (Specific, but not equal to Disease Activity)

16

U1RNP

MCTD (mixed connective tissue disease)

17

ds-DNA

Renal SLE (Equal to Disease Activity)

18

Jo1 / Synthetase

Inflammatory Myopathy (Synthetase Syndrome)

19

SRP

Inflammatory Myopathy ( Decrease Prog)

20

Mi-2

Inflammatory Myopathy (Increase Prog)

21

P-Lipid (LA/aCL)

HyperCoag anticardiolipin antibodies = aCL
SLE (Miscarriage, Neuro) lupus anticoagulant = LA

22

cANCA

Granulomatosis with polyangiitis
Wegener’s

23

pANCA

Micro. Polyangitis, Churg-Strauss, IBD

24

Serial ESR/CRP

RA