Flashcards in Antibody Structure and Function Deck (14):
What antibody exists in two forms?
IgA, secretory form and non-secreted form
What is the structure of antibody?
two light chains, two heavy chains
Which antibody has the shortest half life?
Which antibodies neutralize?
What antibody opsonizes?
What antibodies activate complement?
What antibody transports across epithelium (to gut, resp tract, urinary tract, mother's milk)?
What antibody can transport across the placenta?
Can IgM participate in opsonization? Why or why not?
No, not without complement because immune cells do not have IgM receptors
What antibodies have a J chain?
IgM (pentamer joined by J chain), IgA secretory form
What is the T piece?
The secretory piece of IgA, resists acid hydrolysis
What does papain digest?
yields three fragments, 2 Fab, 1 Fc
cleaves the interchain disulfide bonds
What does pepsin digest?
yields 2 fragments, 1 F(ab)2, 1 Fc