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Flashcards in antiparasites Deck (14):
1

list the drugs that counter intestinal parasites

paromomycin (an aminoglycoside antibiotic)

i.e versus giardia lamblia, cryptosporidia, entamoeba histolytica

2

name a drug used for ectoparasites

permethrin

3

name 2 antihelminths

1. pyrantel pamoate
2. ivermectin

4

paromomycin MOA

IRREVERSIBLY binds 30S ribosome

5

paromomycin indications

intestinal parasites

6

pyrantel pamoate MOA

cholinesterase inhibitor

7

pyrantel pamoate indications

antihelminth

i.e against enterobius vermicularis and ancylostoma duodenale

8

chloroquine MOA

antimalarial active int he ERYTHROCYTE phase

9

chloroquine indication

P. falciparum/vivax/ovale/malariae/knowlesi

10

atovaquone/proguanil MOA

anti-malarial active in the LIVER and ERYTHROCYTE phases

11

permethrin MOA

alters NEURON SODIUM CHANNELS in ectoparasites causing paralysis and death

12

ivermectin MOA

binds and activates GLUTAMATE-GATED CHLORIDE channels

13

ivermectin indications

strongyloides stercoralis
ascaris lumbricoides
trichuris trichuria

anti-helminth

14

what is the mazzoti reaction

a host inflammatory reaction to the death of parasites after drug administration

fever, hives, asthma, GI upset