Antiplatelets Flashcards Preview

2 Cardiovascular > Antiplatelets > Flashcards

Flashcards in Antiplatelets Deck (9)
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1
Q

Antiplatelet drugs inhibit thrombus formation in veins or arteries?

A

Arteries ( in fast flowing circulation the thrombi are composed of platelets)

2
Q

Is aspirin recommended in primary prevention of CV?

A

No evidence of this with or without diabetes.

There is only evidence in established CV diseases.

3
Q

Before aspirin is given what should be controlled?

What else could you consider prescribing with it?

A

Control high BP

consider PPI if at risk of GI bleed

4
Q

For NSTEMI how long should we dual antiplatelet for?

A

12 months (most benefit in first three months )

5
Q

What dual antiplatelet is given post PCI

For how long

A

Aspirin indefinitely
Clopidogrel for 1 month if elective
For 12 months if as a result of ACS
12 months for drug eluding stent

6
Q

Indications for dipyrimidole 3

A

Diagnostic procedures
Prophylaxis of thromboembolism following prosthetic heart valves
Secondary prevention of stroke/TIA

7
Q

Use of epoprostenol (2)

More of action

A

Inhibit platelets aggregation during renal dialysis when heparin are contraindicated
& for pulmonary hypertension

  • potent vasodilator & glycoprotein inhibitor

(duration of action 3 mins therefore continuous IV infusion)

8
Q

Abciximab, epitifbatide and tirofiban are…. Mode of action

A

Glycoprotein IIb/IIIa inhibitors - prevent platelet aggregation by blocking binding fibrinogen receptors to platelets

(Specialist use)

9
Q

Why should abiciximab only b used once

A

Risk of thrombocytopenia