Antipsychotic Agents and Lithium Flashcards Preview

P Pha T > Antipsychotic Agents and Lithium > Flashcards

Flashcards in Antipsychotic Agents and Lithium Deck (11):
1

The following statements about lithium are true, except?
A. The threshold for toxicity is 2 meq/L
B. Lithium toxicity is treated by hemodialysis
C. May cause Ebstein's anomaly to a pregnant mother
D. Treatment for bipolar disorder
E. Contraindicated for patients with sick sinus syndrome

C

It causes Ebstein's anomaly to the fetus.
Ebstein's anomaly is a congenital heart defect in which the septal and posterior leaflets of the tricuspid valve are displaced towards the apex of the right ventricle of the heart (low implanted tricuspid valve)

2

__________ is effective in some schizophrenic patients resistant tot treatment with other antipsychotics _

Clozapine

3

Typical antipsychotic
SE: corneal and lens deposits

Chlorpromazine (Think: chlor-neal deposits)

4

Typical antipsychotic
SE: retinal deposits

Thioridazine (Think : Thioridazine reTinal deposits

5

Least sedating among typical antipsychotics
SE: NMS

Haloperidol

6

Atypical antipsychotic
Only antipsychotic that reduces risk of suicide
SE: agranulocytosis

Clozapine
(watch it CLOZely for agranulocytosis)

7

Atypical antipsychotic
Uses: somnolence, fatigue, sleep paralysis, hypnagogic hallucinations, cataract, priapism
Not for geriatric patients

Quetiapine (Think Quetiapine Quiet time)

8

Atypical antipsychotic
Only antipsychotic approved for schizophrenia in the youth
SE: hyperprolactinemia

Risperidone
(Think: Ris-pair-idone gives rise to a pair (gynecomastia due to hyperprolactinemia))

9

Atypical antipsychotic
SE: postural hypotension, QT prolongation (torsades)
Increased mortality in elderly patients with dementia-related psychosis

Ziprasidone

10

Least sedating atypical antipsychotic
Little or no tendency to cause hyperglycemia, hyperprolactinemia, or weight gain

Aripiprazole

11

Feature of neuroleptic malignant syndrome (5)
First-line treatment for NMS: _______
Onset: _______

FEVER
Fever
Encephalopathy
Vitals unstable
Elevated CPK
Rigidity

Diphenhydramine
1-3 days

Decks in P Pha T Class (62):