Anxiolytic Agents

Question 1

Inc. catecholamine,
Dec. serotonin (sadness)

Answer 1

Anxiety

Question 2

Bridge Drugs for Anxiety

Answer 2

BZD

Question 3

1st line for Panic disorder

Answer 3

SSRIs

Question 4

Generalized anxiety disorder

Answer 4

SSRIs (Fluoxetine)
SNRIs (Duloxetine)
Buspirone (for unresponsive)

Question 5

Obsessive-compulsive disorder (OCD)

Answer 5

SSRIs

Question 6

Social anxiety disorder &
Post-traumatic stress disorder

Answer 6

1st line tx: CBT
1st line Drug: SSRIs

Question 7

MOA: ↑ the FREQUENCY of Cl- channel opening

Answer 7

BZD

Question 8

MOA: ↑ the DURATION of Cl- channel opening
- more toxic

Answer 8

Barbiturates

Question 9

1st-line drugs for insomnia

Answer 9

Sleeping onset: Zaleplon (or Ramelteon)
Staying asleep: Zolpidem (or Eszopiclone)

Question 10

Phenobarbital is an

Answer 10

Enzyme InDucer

Question 11

Active metabolite of chloral hydrate

Answer 11

Trichloroethanol

Question 12

Anterograde amnesia ‘‘date rape’’

Answer 12

Benzodiazepines (e.g., Flunitrazepam and
Midazolam)