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Flashcards in ARDS Deck (15):
1

2 main steps in ARDS

1. initial insult
2. alveoli fill with fluid

2

cause of alveoli fluid filling

NOT cardiogenic - due to capillary permiability

3

3 pathology phases of ARDS

1. exudative - inflammation and edema
2. proliferative phase -
3. fibrosis

4

what does endotoxin do in

release of tumor necrosis factor and interleukins + cytokines

5

what goes to lung in ARDS

neutrophils - increase cap. permiability

6

3 things that happen with fluid in alveoli

1. decr. vent > V/Q mismatch
2. shunt
3. maintained perfusion bc cytokines cause vasodilation

7

4 ways to treat

1. oxygenate - but not over!
2. treat primary cause
3. vent if required
4. use low tidal volumes (pemissive hypercapnea)

8

5 ways to support in ARDS

1. IV fluids
2. BP support
3. antibiotics
4. nutrition
5. care of endotracheal tube

9

keys to fluids in ARDS

balance is keys - don't dry out too much

10

what lung volumes DON't go down with age

RV

11

what does lung aging resemble

pseudo-emphysema - less elastic as age

12

what happens to vent as age (2)

1. response to hypercapnea blunted
2. blunted perception of dyspnea

13

what happens to perfusion as age

more constricted

14

what happens to A-a gradient as age and why

increases due to thicker alveoli and loss of surface area

15

what happens to chest wall as age

no real evidence of change in compliance without disease

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