Arena-, Bunya-, Borna- Flashcards

(38 cards)

1
Q

Mononegavirales consists of…

A
  • Bornaviridae
  • Arenaviridae
  • Rhabdoviridae
  • Filoviridae
  • Paramyxoviridae
  • Bunyaviridae

(BARF PB)

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2
Q

Bunya-: Etymology

A

Bunyamwera: African region

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3
Q

Bunya-: Morphology

A
  • Segmented -ssRNA genome
  • Helical capsid
  • Enveloped
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4
Q

Bunya-: Resistance

A

Weak

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5
Q

Bunya-: Biological properties

A
  • Baltimore V - Viral transcriptase
  • Zoonotic
  • Rodent reservoir
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6
Q

Bunya-: Antigenic properties

A
  • Good antigens
  • Cross-reaction within genera
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7
Q

Bunya-: Diagnosis

A
  • Isolation
  • IF
  • VN
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8
Q

Bunya-: Genuses

A
  • Orthobunya-
  • Hanta-
  • Nairo-
  • Phlebo-
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9
Q

Orthobunya-: Examples

A
  • Akabane virus
  • Lacrosse virus*
  • Tahyna virus*
  • Inkoo virus*

*Human - Fever, rash, encephalitis

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10
Q

Phlebo-: Example

A

Rift valley fever virus

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11
Q

Nairo-: Examples

A
  • Nairobi sheep fever
  • Crimean-congo haemorrhagic fever
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12
Q

Hanta-: Example

A

Hantaan haemorrhagic fever with the renal syndrome

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13
Q

Arena-: Etymology

A

Arena-: Sand

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14
Q

Arena-: Morphology

A
  • Segmented -ssRNA genome
  • Øcapsid
  • Enveloped
  • Ribosomes inside
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15
Q

Arena-: Resistance

A

Weak

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16
Q

Arena-: Biological properties

A
  • Baltimore V - Viral transcriptase
  • Zoonotic
  • Rodent reservoir
17
Q

Arena-: Antigenic properties

A
  • Good antigens
  • Cross-reactions within the genus
18
Q

Arena-: Diagnosis

A
  • Isolation
  • IF
  • VN
  • IIF
19
Q

Arena-: Genuses

A
  • Old world
  • New world
20
Q

Arena-: Old world examples

A
  • Lymphocytic choriomeningitis virus
  • Lassa-, Mobala-, Mopeia-
21
Q

Arena-: New world example

A
  • Tacaribe-
  • Junin-
  • Machup-
22
Q

Rift valley fever virus

A

Sheep, cattle, zoonotic

  • Abortion
  • Fever
  • Blood
  • Diarrhoea

Mosquito transmitted

23
Q

Nairobi sheep fever

A

Sheep, goat

  • Fever
  • Abortion
  • High mortality

Tick transmitted

24
Q

Crimean-congo haemorrhagic fever

A

Humans

  • Haemorrhage
  • Rash
  • Nephritis
25
Hantaan haemorrhagic fever
Human * Fever * Nephritis * High mortality Rodent reservoir
26
Lymphocytic choriomeningitis virus (LCM)
Europe, USA Human (Pet hamsters → Children) * Paresis * Paralysis
27
Lassa-; Mobala-; Mopeia virus
Africa Humans, primates * Haemorrhage * Encephalitis
28
Tacaribe-; junin-; Machup virus
S. America Rodent → Human * Haemorrhage * Encephalitis
29
*Borna-*: Morphology
* -ssRNA genome * Helical capsid * Enveloped
30
*Borna-*: Resistance
Weak
31
*Borna-*: Biological properties
* Baltimore V - _Multiplication in the nucleus_ * Zoonotic * Rodent reservoir
32
*Borna-*: Antigenic properties
Good antigens
33
*Borna-*: Diagnosis
* _Clinical symptoms_ * _Histopathology lesions_ * _RT-PCR_
34
*Borna-*: Genus
Bornavirus
35
*Borna-*: Examples
* Bornavirus * Avian bornavirus
36
Bornavirus
Euryxen * Encephalitis * Encephalosis (disease of brain)
37
Avian bornavirus
Parrot * Proventricular dilation disease
38
*Bunya-*: Transmission
Arbovirus (Except Hanta-)