Arena-, Bunya-, Borna-

Question 1

Mononegavirales consists of…

Answer 1

• Bornaviridae
• Arenaviridae
• Rhabdoviridae
• Filoviridae
• Paramyxoviridae
• Bunyaviridae

(BARF PB)

Question 2

Bunya-: Etymology

Answer 2

Bunyamwera: African region

Question 3

Bunya-: Morphology

Answer 3

• Segmented -ssRNA genome
• Helical capsid
• Enveloped

Question 4

Bunya-: Resistance

Answer 4

Weak

Question 5

Bunya-: Biological properties

Answer 5

• Baltimore V - Viral transcriptase
• Zoonotic
• Rodent reservoir

Question 6

Bunya-: Antigenic properties

Answer 6

• Good antigens
• Cross-reaction within genera

Question 7

Bunya-: Diagnosis

Answer 7

• Isolation
• IF
• VN

Question 8

Bunya-: Genuses

Answer 8

• Orthobunya-
• Hanta-
• Nairo-
• Phlebo-

Question 9

Orthobunya-: Examples

Answer 9

• Akabane virus
• Lacrosse virus*
• Tahyna virus*
• Inkoo virus*

_{*Human - Fever, rash, encephalitis}

Question 10

Phlebo-: Example

Answer 10

Rift valley fever virus

Question 11

Nairo-: Examples

Answer 11

• Nairobi sheep fever
• Crimean-congo haemorrhagic fever

Question 12

Hanta-: Example

Answer 12

Hantaan haemorrhagic fever with the renal syndrome

Question 13

Arena-: Etymology

Answer 13

Arena-: Sand

Question 14

Arena-: Morphology

Answer 14

• Segmented -ssRNA genome
• Øcapsid
• Enveloped
• Ribosomes inside

Question 15

Arena-: Resistance

Answer 15

Weak

Question 16

Arena-: Biological properties

Answer 16

• Baltimore V - Viral transcriptase
• Zoonotic
• Rodent reservoir

Question 17

Arena-: Antigenic properties

Answer 17

• Good antigens
• Cross-reactions within the genus

Question 18

Arena-: Diagnosis

Answer 18

• Isolation
• IF
• VN
• IIF

Question 19

Arena-: Genuses

Answer 19

• Old world
• New world

Question 20

Arena-: Old world examples

Answer 20

• Lymphocytic choriomeningitis virus
• Lassa-, Mobala-, Mopeia-

Question 21

Arena-: New world example

Answer 21

• Tacaribe-
• Junin-
• Machup-

Question 22

Rift valley fever virus

Answer 22

Sheep, cattle, zoonotic

• Abortion
• Fever
• Blood
• Diarrhoea

Mosquito transmitted

Question 23

Nairobi sheep fever

Answer 23

Sheep, goat

• Fever
• Abortion
• High mortality

Tick transmitted

Question 24

Crimean-congo haemorrhagic fever

Answer 24

Humans

• Haemorrhage
• Rash
• Nephritis

Question 25

Hantaan haemorrhagic fever

Answer 25

Human * Fever * Nephritis * High mortality Rodent reservoir

Question 26

Lymphocytic choriomeningitis virus (LCM)

Answer 26

Europe, USA Human (Pet hamsters → Children) * Paresis * Paralysis

Question 27

Lassa-; Mobala-; Mopeia virus

Answer 27

Africa Humans, primates * Haemorrhage * Encephalitis

Question 28

Tacaribe-; junin-; Machup virus

Answer 28

S. America Rodent → Human * Haemorrhage * Encephalitis

Question 29

*Borna-*: Morphology

Answer 29

* -ssRNA genome * Helical capsid * Enveloped

Question 30

*Borna-*: Resistance

Answer 30

Weak

Question 31

*Borna-*: Biological properties

Answer 31

* Baltimore V - _Multiplication in the nucleus_ * Zoonotic * Rodent reservoir

Question 32

*Borna-*: Antigenic properties

Answer 32

Good antigens

Question 33

*Borna-*: Diagnosis

Answer 33

* _Clinical symptoms_ * _Histopathology lesions_ * _RT-PCR_

Question 34

*Borna-*: Genus

Answer 34

Bornavirus

Question 35

*Borna-*: Examples

Answer 35

* Bornavirus * Avian bornavirus

Question 36

Bornavirus

Answer 36

Euryxen * Encephalitis * Encephalosis (disease of brain)

Question 37

Avian bornavirus

Answer 37

Parrot * Proventricular dilation disease

Question 38

*Bunya-*: Transmission

Answer 38

Arbovirus (Except Hanta-)