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Flashcards in Asthma Deck (27):
1

Effect of beta-2 agonist

bronchodilation

2

Boxed warning of LABA as monotherapy in asthma

Increased risk of asthma-related deaths and should only be used in conjunction with ICS

3

Serevent Diskus

salmerterol

4

Perforomist

formoterol nebulizer solution

5

Symbicort

formoterol + budesonide

6

Dulera

mometasone + formoterol

7

Bevespi

glycopyrrolate + formoterol

8

QVAR

beclomethasone
Do not shake

9

Pulmicort Flexhaler

budesonide

10

Alvesco

ciclesonide
Do not shake

11

Aerospan HFA

flunisolide

12

Flovent Diskus or HFA

fluticasone

13

Arnuity Ellipta

fluticasone furoate

14

Breo Ellipta

fluticasone furoate + vilanterol

15

Asmanex HFA or Twisthaler

mometasone

16

Dulera

mometasone + formoterol

17

Accolate

zafirlukast

18

Singulair

montelukast

10mg PM
6-14yo: 5mg PM
1-5yo: 4mg PM

19

Zyflo

zileuton

20

Leukotriene receptor antagonists MOA

Target an inflammatory pathway in asthma

Zafirlukast - inhibits LTD4 + LTE4
Singulair - ihibits LTD4
Zileuton - 5-lipoxygenase inhibitor inhibits leukotriene formation

21

Theo-24 or Theochron or Elixophyllin

theophylline
caffeine and 3-methylxanthine are active metabolites
Blocks PDE causing increase in cAMP to promote release of epinephrine from adrenal medulla to cause bronchodilation.

22

Therapeutic range of theophylline

5-15 mcg/mL
measure peak level after 3 days of oral dosing

23

Conversion from aminophylline to theophylline

Multiply by 0.8

24

Xolair

omalizumab

subcutaneous
always given in healthcare setting

25

Peak flow meter zones

GREEN 80-100%
YELLOW 50-80%
RED <50%

26

HFA inhaler instructions

Shake for 5 seconds before use.
Breathe in slowly and deeply.
Hold breath as long as possible.

27

DPI inhaler instructions

Get dose ready and hold in hand away from mouth.
Breath out fully away from mouth.
Breathe in quickly and deeply.