Asthma and COPD Questions

Question 1

MOA for asthma drugs for Asthma and COPD

Tiotropium bromide: muscarinic receptor antagonist

Answer 1

a. True.

Question 2

MOA for asthma drugs for Asthma and COPD

Montelukast: beta 2 adrenoceptor agonist

Answer 2

b. False. Leukotriene receptor antagonist

Question 3

MOA for asthma drugs for Asthma and COPD

Formoterol: beta 2 antagonist

Answer 3

c. False. Agonist

Question 4

MOA for asthma drugs for Asthma and COPD

Theophylline: inhibition of phosphodiesterase

Answer 4

d. True

Question 5

MOA for asthma drugs for Asthma and COPD

Budesonide: inhibit gene transcription

Answer 5

e. True. CS

Question 6

Asthma drugs:

a. Theophylline increases risk of bradycardia in the elderly

Answer 6

a. False. Tachycardia

Question 7

b. A short course of oral prednisone (7-14 days) is used to treat acute exacerbations of asthma

Answer 7

b. False. ?

Question 8

c. Inhaled beclomethasone increases the risk of oropharyngeal candidiasis

Answer 8

c. True

Question 9

d. Oral salbutamol causes tremor

Answer 9

d. True

Question 10

e. Smoking increases plasma concentrations of theophylline

Answer 10

e. False. Decreases  increased P450 activity

Question 11

Asthma and COPD drugs adverse effects:

a. Tiotropium bromide: tremor

Answer 11

a. False: Muscarinic antagonist dry mouth, bitter taste, paradoxical bronchoconstriction, urinary retention and constipation (less likely)

Question 12

b. Montelukast churg-strauss vasculitis

Answer 12

b. True (but rare)

Question 13

c. Oral salbutamol: sedation

Answer 13

c. False.

Question 14

d. Theophylline: seizures

Answer 14

d. True

Question 15

e. Fluticasone: sore throat

Answer 15

e. True. ICS

Question 16

Drugs used in the treatment of Asthma and COPD

a. Formoterol has a faster onset of action than salbutamol

Answer 16

a. False. Formoterol is LABA and salbutamol is a SABA

Question 17

b. Montelukast is used in the management of exercise induced asthma

Answer 17

b. True

Question 18

c. Theophylline clearance is reduced in the elderly

Answer 18

c. True

Question 19

d. Tiotropium bromide causes dry mouth

Answer 19

d. True. Muscarinic antagonist

Question 20

e. IV hydrocortisone is used in the treatment of acute severe ashtma

Answer 20

e. True

Question 21

Asthma/ COPD

a. Inhaled ipratropium bromide has a longer duration of action than tiotropium bromide

Answer 21

a. False, tiotropium is long acting

Question 22

b. Montelukast is used in the treatment of exercise induced asthma

Answer 22

b. True

Question 23

c. Inhaled salbutamol has a slower onset of action than inhaled salmeterol

Answer 23

c. False

Question 24

d. Salmeterol is preferred to salbutamol in an acute attack of asthma

Answer 24

d. False

Question 25

e. Inhaled beclomethasone causes oropharyngeal candidiasis

Answer 25

e. True

Question 26

Drug used in the management of asthma and COPD | a. Fluticasone is b2 receptor agonist

Answer 26

a. False. CS

Question 27

b. Clearance of theophylline is reduced in patients over the age of 55

Answer 27

b. True

Question 28

c. Inhaled ipratropium bromide causes dry mouth as a side effect

Answer 28

c. True

Question 29

d. Montelukast causes nightmares as an adverse effect

Answer 29

d. True

Question 30

e. Salbutamol causes bradycardia as an adverse effect

Answer 30

e. False. Tachycardia