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Flashcards in Asthma and COPD Questions Deck (30)
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1

MOA for asthma drugs for Asthma and COPD
Tiotropium bromide: muscarinic receptor antagonist

a. True.

2

MOA for asthma drugs for Asthma and COPD

Montelukast: beta 2 adrenoceptor agonist

b. False. Leukotriene receptor antagonist

3

MOA for asthma drugs for Asthma and COPD
Formoterol: beta 2 antagonist

c. False. Agonist

4

MOA for asthma drugs for Asthma and COPD

Theophylline: inhibition of phosphodiesterase

d. True

5

MOA for asthma drugs for Asthma and COPD
Budesonide: inhibit gene transcription

e. True. CS

6

Asthma drugs:
a. Theophylline increases risk of bradycardia in the elderly

a. False. Tachycardia

7

b. A short course of oral prednisone (7-14 days) is used to treat acute exacerbations of asthma

b. False. ?

8

c. Inhaled beclomethasone increases the risk of oropharyngeal candidiasis

c. True

9

d. Oral salbutamol causes tremor

d. True

10

e. Smoking increases plasma concentrations of theophylline

e. False. Decreases  increased P450 activity

11

Asthma and COPD drugs adverse effects:
a. Tiotropium bromide: tremor

a. False: Muscarinic antagonist dry mouth, bitter taste, paradoxical bronchoconstriction, urinary retention and constipation (less likely)

12

b. Montelukast churg-strauss vasculitis

b. True (but rare)

13

c. Oral salbutamol: sedation

c. False.

14

d. Theophylline: seizures

d. True

15

e. Fluticasone: sore throat

e. True. ICS

16

Drugs used in the treatment of Asthma and COPD
a. Formoterol has a faster onset of action than salbutamol

a. False. Formoterol is LABA and salbutamol is a SABA

17

b. Montelukast is used in the management of exercise induced asthma

b. True

18

c. Theophylline clearance is reduced in the elderly

c. True

19

d. Tiotropium bromide causes dry mouth

d. True. Muscarinic antagonist

20

e. IV hydrocortisone is used in the treatment of acute severe ashtma

e. True

21

Asthma/ COPD
a. Inhaled ipratropium bromide has a longer duration of action than tiotropium bromide

a. False, tiotropium is long acting

22

b. Montelukast is used in the treatment of exercise induced asthma

b. True

23

c. Inhaled salbutamol has a slower onset of action than inhaled salmeterol

c. False

24

d. Salmeterol is preferred to salbutamol in an acute attack of asthma

d. False

25

e. Inhaled beclomethasone causes oropharyngeal candidiasis

e. True

26

Drug used in the management of asthma and COPD
a. Fluticasone is b2 receptor agonist

a. False. CS

27

b. Clearance of theophylline is reduced in patients over the age of 55

b. True

28

c. Inhaled ipratropium bromide causes dry mouth as a side effect

c. True

29

d. Montelukast causes nightmares as an adverse effect

d. True

30

e. Salbutamol causes bradycardia as an adverse effect

e. False. Tachycardia