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Respiratoir systeem > Astma > Flashcards

Astma Flashcards

1
Q

Hoeveel patienten

A

300 miljoen.
5-16% vd mensen

Ontstaat vaak op kinderleeftijd
Mensne overlijden nog steeds

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2
Q

Astma aandoening

A

Chronische inflammatoire luchtwegaandoening, luchtweghyperreactiviteit, reversibele luchtwegobstructie

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3
Q

Luchtweghyperreactiviteit

A

Reageren op aspecifieke prikkels; mistig weer, ANAMNESE BELANGRIJK

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4
Q

Chronische inflammatie

A

Eosinophiele granulocyt

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5
Q

Chronische inflammatie

A

Eosinophiele granulocyt

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6
Q

Verschillende astma fenotypes

A

Th2 hoog en laag

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7
Q

Atopie

A

Verhoogd IgE

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8
Q

Factoren voor ontstaan en invloed

A

V > M, Overgewicht, genetisch.

Allergenen, infectie, blootstelling op werk, emotie, dieet, roken, medicatie

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9
Q

Kenmerkend voor astma

A

Verlengd piepend experium

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10
Q

Astma X-thorax?

A

Normaal

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11
Q

Aanvullend onderzoek astmaN

A

Lab; eosinophilie, IgE verhoogd, RAST
Eventueel huidpriktest
Longfunctie; reversibiliteit
Metacholine provacatie test

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12
Q

Diffusie bij astma?

A

Normaal

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13
Q

Behandeling astma

A

Expositie vermijden

beta symptaticomimetica!!!!!!!!!!
inhalatie corticosteroiden!!!!!!!!!!
anticholinergica
leukotrieen antagonisten
systemische corticosteroiden
biologicals
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14
Q

Inhalatie corticosteroiden

A

Basis behandeling; ontstekingsremmer.

Zo nodig salbutamol; B sympaticomimetica (relaxatie bronchiale gladde spierweefsel) –> neem je bij inspanning

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15
Q

Stap 2 in behandeling AStma

A

ICS + LABA

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16
Q

Exacerbatie astma

A

Na BLWI

Verhoogd poCO2 is teken van uitputting

17
Q

Extreem ernstige astma

A

Biologicals

Omalizumab (anti-IgE) - Mepolizumab (anti-IL5) - Benralizumab (anti-IL5R) - Dupilumab (anti-IL4/13).

Respiratoir systeem (11 decks)

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