Autoantibodies Flashcards

1
Q

Anti-IgG antibodies

A

Rheumatoid Arthritis

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2
Q

Anti-citrullinated protein antibodies (ACPA)

A

Rheumatoid Arthritis

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3
Q

Anti-centromere

A

CREST scleroderma

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4
Q

Anti-Scl-70

A

diffuse SCLeroderma

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5
Q

Anti-histone

A

Drug-induced lupus

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6
Q

Anti-nuclear antibodies (ANA)

A

SLE

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7
Q

Anti-Smith

A

SLE (more specific)

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8
Q

Anti-dsDNA

A

lupus nephritis

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9
Q

Anti-Jo-1

A

polymyositis/dermatomyositis

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10
Q

Anti-SSA (anti-Ro)

A

Sjogren

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11
Q

Anti-SSB (anti-La)

A

Sjogren

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12
Q

Anti-U1-RNP

A

Mixed Connective Tissue Disease

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13
Q

Anti-desmoglein

A

Pemphigus Vulgaris

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14
Q

Anti-acetylcholine receptor

A

Myasthenia Gravis

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15
Q

Anti-endomysial (anti-tissue transglutaminase)

A

Celiac

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16
Q

Anti-gliadin

A

Celiac

17
Q

Anti-mitochondrial

A

Primary Biliary Cirrhosis

18
Q

Anti-smooth muscle

A

autoimmune hepatitis

19
Q

Anti-glutamate decarboxylase

A

type 1 diabetes

20
Q

Anti-thyrotropin receptor

A

graves

21
Q

Anti-thyroid peroxidase (anti-TPO)

A

Hashimoto

22
Q

Anti-thyroglobulin

A

Hashimoto

Graves

23
Q

Anti-basement membrane

A

good pasture’s

24
Q

c-ANCA

A

Granulomatosis w/ Polyangiitis (Wegener’s)

25
Q

p-ANCA

A

Pauci-immune crescentic glomerulonephritis
Churg-Strauss Syndrome
Microscopic Polyangiitis