Autonomic nervous system Flashcards

1
Q

Where are visceral motor nuclei located?

A

Hypothalamus.

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2
Q

Structure of parasympathetic nerves in relation to ganglions?

A

Long pre ganglionic nerve, short post ganglionic nerve.

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3
Q

Structure of sympathetic nerves in relation to ganglions?

A

Short pre ganglionic nerve, long post ganglionic nerve.

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4
Q

Why do sympathetic nerve have a different structure in relation to ganglions compared to parasympathetic nerves?

A

Sympathetic response generally needs to be more coordinated. Nerves meet together before firing off.

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5
Q

What is the one exception to the two neurone arrangement in the autonomic nervous system?

A

Adrenal gland. One sympathetic nerve attached to adrenal gland.

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6
Q

In pre ganglionic nerves what neurotransmitter is released?

A

Acetylcholine.

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7
Q

In post ganglionic nerves what neurotransmitter is released in parasympathetic?

A

Acetylcholine

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8
Q

In post ganglionic nerves what neurotransmitter is released in sympathetic?

A

Noradrenaline.

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9
Q

What branch of nerves in the autonomic nervous system go to the lungs?

A

Parasympathetic only.

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10
Q

What receptor is found at parasympathetic and sympathetic ganglia?

A

Nicotinic acetylcholine receptor.

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11
Q

What receptor is found in the adrenal medulla?

A

Nicotinic acetylcholine receptor.

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12
Q

How does the sympathetic nerves liberate catecholamines from the adrenal medulla?

A

Acetylcholine released by the sympathetic nerves activates nicotinic acetylcholine receptors on adrenal medulla. Release of catecholamines into bloodstream.

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13
Q

What kind of receptor is nicotinic acetylcholine receptor?

A

Ion channel receptor

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14
Q

What binds to the nicotinic acetylcholine receptor?

A

Acetylcholine.

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15
Q

What receptor is found on organs that parasympathetic nerves and adrenergic nerves modulate?

A

Muscarinic receptor in parasympathetic and adrenergic receptor in sympathetic (G coupled protein receptors).

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16
Q

How can the breakdown of acetylcholine take place?

A

Broken down by acetylcholinesterase in synapse and choline is take up by choline uptake protein on presynaptic terminal or glial cell.

17
Q

How is acetylcholine made?

A

Acetyl CoA, choline and choline acetyl transferase.

18
Q

How is noradrenaline made?

A

Tyrosine hydroxylated to DOPA, DOPA decarboxylated to dopamine. Dopamine packed into a vesicle with dopamine β hydroxylase. Noradrenaline is the product.

19
Q

How does breakdown of noradrenaline take place?

A

Taken up by glial cell or presynaptic terminal. Broken down by monoamine oxidase in presynaptic terminal and catechol o methyl transferase in glial cell.

20
Q

What converts noradrenaline converted to adrenaline?

A

Phenylethanol methyl transferase.