Autonomic Pharmacology Flashcards Preview

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Flashcards in Autonomic Pharmacology Deck (15):
1

True or False.
The enteric nervous system consists of the submucous plexus (Meissner plexus) and the myenteric plexus (plexus of Auerbach).

True

2

What are the cranial nerves which are parasympathetic?

CN 10, 9, 7, 3
Think: 1973 PCN

3

Organs which are primarily sympathetic (2)

sweat glands
blood vessels

4

Sympathetic or parasympathetic nervous system?
Paravertebral chains that lie along the spinal column, some along the anterior aspect of the abdominal aorta

Sympathetic

Think: Excited kaya ang lapit ng ganglion sa pinanggalingan (spinal cord).

5

Sympathetic or parasympathetic nervous system?
Short Pre ganglionic fibers, long postganglionic fibers

Sympathetic

6

True or False.
All sphincters use alpha-1 receptors for their sympathetic effects.

True

7

Which of the following drugs inhibit transport of choline to be used for the synthesis of acetylcholine?
A. Hemicholinium
B. Vesamicol
C. Botulinum
D. Neostigmine
E. Carbamates
F. Organophosphates

A. Hemicholinium

8

Which of the following drugs inhibit transport of acetylcholine into vesicles for storage by vesicle-associated transporter (VAT)?
A. Hemicholinium
B. Vesamicol
C. Botulinum
D. Neostigmine
E. Carbamates
F. Organophosphates

B. Vesamicol

9

Which of the following drugs alter synaptobrevins to prevent release of acetylcholine?
A. Hemicholinium
B. Vesamicol
C. Botulinum toxin
D. Neostigmine
E. Carbamates
F. Organophosphates

C. Botulinum toxin

10

Which of the following drugs inhibit the degradation of acetylcholine into choline and acetate by acetylcholinesterase?
A. Hemicholinium
B. Vesamicol
C. Botulinum
D. Neostigmine
E. Carbamates
F. Organophosphates

D, E, F

11

What cholinoceptor(s) is/are being referred to?
Gq-coupled mechanism
Increase in IP3, DAG cascade
Found in nerve endings

M1

12

What cholinoceptor(s) is/are being referred to?
Gi-coupled mechanism
Decrease in cAMP; activates K channels
Found in the heart and some nerve endings

M2

13

What cholinoceptor(s) is/are being referred to?
Gq-coupled mechanism
Increase in IP3, DAG cascade
Found in effector cells, smooth muscle, glands, and endothelium

M3

14

What cholinoceptor(s) is/are being referred to?
Mechanism via sodium channels
Depolarizes, evokes action potential
Found in ANS ganglia

Nn

15

What cholinoceptor(s) is/are being referred to?
Mechanism via sodium channels
Depolarizes, evokes action potential
Found out n neuromuscular endplate

Nm

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