B2 W3 Flashcards

1
Q

Phase 1

A

Phase of cardiac action potential where sodium channels are inactivated and fast potassium efflux occurs

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2
Q

Which leads give an anterior view of heart?

A

V3 and V4

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3
Q

Septal view of heart from leads

A

V1 and V2

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4
Q

Phase 3 of action potential

A

Phase of action potential where Calcium channels inactive and delayed K+ efflux?

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5
Q

Which aortic sinus does not drain into one of the coronary arteries?

A

Right posterior

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6
Q

Troponin complex that inhibits myosin binding

A

Troponin I

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7
Q

Ejection fraction

A

Fraction of EDV ejected out by each ventricle

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8
Q

ECG which provides lateral view of the heart

A

V5 and V6

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9
Q

Cardiac axis

A

Direction of electrical current flow in the heart when ventricles are contracting

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10
Q

What separates the rough and smooth muscle of the right atria

A

Crista terminalis

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11
Q

Which coronary veins drain into the RA?

A

Great, middle, small and oblique coronary vein- this is via the coronary sinus

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12
Q

What demarcates marks the crista terminalis?

A

Sulcus terminalis

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13
Q

Lateral view of heart from leads

A

V5 and V6

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14
Q

Inferior view of heart

A

Lead III

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15
Q

Which arteries fill during diastole?

A

Only the coronary arteries which are thin. They cannot fill during systole.

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16
Q

ST segment

A

Isoelectric line between depolarisation and repolarisation

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17
Q

What type of receptor is an adrenergic receptor?

A

G-protein coupled receptor

18
Q

What is the effect of noradrenaline on SAN receptors?

A

G protein phosphorylates phospholamban to induce Ca2+ release following cAMP cascade

19
Q

What separates arterial and venous blood flow?

A

Transverse pericardial sinus

20
Q

Which leads provide inferior view of the heart

A

Lead II, Lead III and avF

21
Q

What does the left aortic sinus give rise to?

A

Left coronary artery: this splits into a LAD and a left circumflex and marginal artery

22
Q

WHat does the right aortic sinus give rise to?

A

Right coronary artery which splits into RPD (right posterior descending) and right marginal artery

23
Q

What is normal cardiac axis?

A

-30 to +90

24
Q

Effect of Digoxin

A

Increases inotropy and reduces chronotropy. Reduced use due to toxicity,

25
Which leads have positive deflection and lateral heart view?
Lead avL, V5, V6 and I- these also provide a lateral view
26
Isovolumetric ventricular relaxation
Ventricles relax and pressure falls so semilunar valves close
27
Which veins drain the heart chambers?
Thesbian veins- smallest veins
28
What returns calcium to SR following contraction?
SERCA (Sarcoendoplasmic reticulum ATPASE)
29
What is the rough muscle of the right atria?
Musculi pectinati
30
What is the smooth muscle of the RA?
Sinous venarum
31
Which vein corresponds to the marginal coronary artery?
Small cardiac vein
32
Oblique pericardial sinus
What is the blind recess caused by pericardial reflections off the pulmonary veins and inferior vena cava?
33
Length of atrial systole?
0.1 seconds
34
How many pulmonary veins drain into Left Atria?
4
35
Which vein descends from the left atria?
Oblique coronary vein
36
Time between two QRS complex
RR interval
37
Chordae tendinae
Connects the papillary muscles to the valve
38
What inhibits binding of myosin?
Troponin I
39
Anterior coronary vein
Drains blood from R ventricle into R atria
40
Which calcium channels open during depolarisation?
L-type Calcium channels
41
Digoxin
Inhibits Na+/K+ ATPase pump. Increases intracellular sodium to cause Na+/Ca2+ exchanger to increase intracellular Ca2+ levels