B2 W4 Flashcards

1
Q

SVC

A

Superior vena cava comes from the common cardinal ceins

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2
Q

What joins the endocardial cushions to separate the ventricles?

A

Interventricular septum

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3
Q

Ventral aorta function

A

Ventral aorta joins the primitive heart tube and fuses to form the aortic sac.

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4
Q

Low pressure receptors

A

Stretch receptors in atria that cause blood pressure to fall. These are part of the natriuretic peptide system

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5
Q

Which arches disappear after pharyngeal arch 5?

A

Arch 1 and 2

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6
Q

Which pharyngeal aortic arches give rise to the vessels?

A

Pharyngeal arch 3, 4 and 6

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7
Q

What is the resistance to flow of liquid?

A

Viscosity

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8
Q

Which receptors are involved in short term control of BP?

A

Chemoreceptors/ Baroreceptors in the carotid artery and aortic arch.

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9
Q

What does the primitive ventricle give rise to?

A

Trabeculated (rough) R + L ventricles

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10
Q

What is the hormonal system for renal control of low blood pressure?

A

Renin-angiotensin-aldosterone

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11
Q

What gives rise to left subclavian artery?

A

Left 7th cervical intersegmental artery

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12
Q

What is the formation of new blood vessels?

A

Vasculogenesis. Angioblasts form islands and cords and canalisation occurs

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13
Q

Separate atria from ventricles during development

A

Atrioventricular endocardial cushions

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14
Q

Sinous venosus

A

Sinous venosus Gives rise to the smooth Right atrium, coronary sinus and oblique vein of LA

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15
Q

Where does the heart develop from?

A

Primary heart field

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16
Q

Primary heart field

A

Where heart develops from. Atria are laterally deposited and ventricular cells are medially deposited

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17
Q

What gives rise to the pulmonary artery?

A

6th pharyngeal arch

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18
Q

What is Pharyngeal arch 4?

A

Comes from the ventral aortic sac. Gives rise to aortic arch.

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19
Q

Which side does the heart loop towards during development?

A

Right side

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20
Q

Angioblastic cord

A

Angioblastic cords paired epithelial strands which canalise into the heart tubes.

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21
Q

What is the effect of prostaglandin?

A

Vasodilator which increases the GFR and reduce Na+ reabsorption

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22
Q

Increases blood pressure by acting as a potent vasoconstrictor and promotes aldosterone release

A

Angiotensin II

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23
Q

Which vessels are pressure reservoirs?

A

Arteries

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24
Q

Natriuretic peptide

A

Atrial natriuretic peptide Synthesised and stored by cardiomyocytes, released when BP is high to lower it

25
What gives rise to the external carotid artery
Pharyngeal arch 3
26
How are substances exchanged across capillary walls?
Diffusion, transcytosis and bulk flow
27
Bradykinin
Potent vasodilator broken down by ACE to increase BP
28
What are the metarteriole vascular shunts which control flow into the capillaries?
Precapillary sphincters
29
Angiogenesis
Angiogenesis Formation of new blood vessels from pre-exiting blood vessels by budding and branching. Occurs during wound healing.
30
Mechanorecepotrs that detect blood pressure
Baroreceptors
31
What is the consequence of Atrial septal defect?
Causes frequent respiratory infections, difficulty breathing and heart palpitations
32
Transcytosis
Transport where Substances in plasma are enclosed in pinocytic vesicles that enter endothelial cells by endocytosis and exit to the other side to other tissue by exocytosis
33
Aorticopulmonary septum
Spiral that allows blood to bypass the lungs and joins the pulmonary artery with aorta
34
Opening between atria which gets closed off by the descending septum primum
Foramen primum
35
Vasomotor center
Area in the medulla which regulates blood pressure via vasodilation
36
Which vessels have the highest cross sectional area?
Capillaries
37
Dorsal aorta
Dorsal aorta Which blood vessels which provides nutrient rich blood to the body tissues in the embryo.
37
Hemiangioblast
Hemiangioblast derived from mesoderm and ectoderm that produces blood cells
38
Stroke volume
Blood ejected from the left ventricle of the heart in one contraction, determined by end diastolic volume, end systolic volume and preload, contractility and after load.
39
Vasculogenesis
Formation of new blood vessels from angioblasts form islands and canals for canalisation
40
Aortic arch
Aortic sac, left aortic horn and left 4th arch artery
41
Bulbos cordus
Smooth Left and Right ventricles -> includes conus arteriosus, outflow tract and infundibulum
42
Truncus arteriosus
Ascending aorta and pulmonary trunk
43
Primitive ventricle
Trabeculated L + R ventricle
44
Primitive atria
Rough L + R atria
45
Sinus venosus
Smooth R atria, coronary sinus and oblique vein of L atria
46
L+ R differentiation of the heart
Cardiac looping
47
Allows communication between the atria
Foramen secundum
48
Allows blood to bypass the lungs and joins the pulmonary artery and aorta
Aorticopulmonary septum
49
What regulates blood flow into tissues in response to demand?
Pre-capillary sphincters
50
Aldosterone release
Adrenal cortex via action of angiotensin II
51
ADH release
Posterior pituitary gland
52
What ensures blood flow around the body?
Pressure
53
Venous return is caused by...
Respiratory pump, muscular pump, gravity adn sympathetic venoconstriction
54
What carries blood from foetus to placenta?
Umbilical vein
55
Transcytosis
Substances in plasma are enclosed in pinocytic vesicles which enter via endocytosis into tissues and exit to the other side by exocyotosis
56
Preload
Volume in the heart pre-contraction, affected by venous returnwwhich affects blood end diastolic volume
57
Endocardium
Inner lining of the heart formed of simple squamous epithelia