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Bacteriology Exam 1 > Bacillus > Flashcards

Flashcards in Bacillus Deck (18):
1

Shape?

Large square-end rods in chains

2

Oxygen?

Facultative anaerobes or aerobes

3

Do Bacillus form endospores?

Yes

4

Which species of Bacillus is the only non-motile species?

B. anthracis

5

Which Bacillus species is an obligate mammal parasite?

B. anthracis

6

What animals are most often affected by Bacillus?

Cattle

7

What is the source of infection?

Ingestion of soil contaminated with spores

8

What factors are needed for Bacillus virulence?

Capsule and tripartite anthrax toxin

9

What are the three parts of the tripartite anthrax toxin?

PA, EF, LF

10

Used for translocation into the cell

Protective antigen: Cell binding factor

11

Increases cAMP to cause edema

Edema factor: Calmodulin-dependent adenylate cyclase

12

Causes cell death and tissue injury and shock (necrosis and hemorrhage)

Lethal Factor: Zinc metalloprotease

13

What are 2 predisposing factors that increase exposure of animals to anthrax spores?

Previous anthrax history and buried carcasses and repeated cycles of flooding and evaporation

14

What is the most common mode of infection?

Ingestion

15

What PM indicators suggest anthrax infection?

Bleeding from orifices, splenomegaly

16

Is anthrax reportable?

Yes

17

What bio-safety level is anthrax?

BSL-3

18

What disease does anthrax cause in humans?

Woolsorter's disease