Bacte Lec: Yersinia

Question 1

How many species of Yersinia?

Answer 1

Seven species of Yersinia

Question 2

is important cause of animal disease.

Answer 2

Y. pseudotuberculosis

Question 3

Cause of plague-like disease in guinea pigs, sometimes rats and occasionally other rodents, rare infections in other animals.

Answer 3

YERSINIA PSEUDOTUBERCULOSIS

Question 4

Pleomorphic, varies from coccoid to bacilli 5 um or more long

Answer 4

YERSINIA PSEUDOTUBERCULOSIS

Question 5

T/F: Y. pseudotuberculosis is sometimes bipolar stained?

Answer 5

True

Question 6

Colony description of Y. pseudotuberculosis

Answer 6

Colonies non-hemolytic, 0.1 to 1.0 mm, translucent and granular

Question 7

Optimum growth temperature Y. pseudotuberculosis

Answer 7

28 C

Question 8

T/F: Y. pseudotuberculosis does not ferment glucose

Answer 8

False: Ferments glucose and some other carbohydrates but produces little or no gas.

Question 9

Y. pseudotuberculosis produces urease?

Answer 9

Does not produce urease.

Question 10

Important virulence factor of Y. pseudotuberculosis

Answer 10

F1 - enveloped antigen

Question 11

F1 antigen is composed of?

Answer 11

composed of protein and carbohydrates

Question 12

T/F: Plasmid encoded X and B antigens, also found in Y. pseudotuberculosis and Y. pestis

Answer 12

False: Plasmid encoded V and W antigens, also found in Y. pseudotuberculosis and Y. pestis

Question 13

Y. pseudotuberculosis usually found in?

Answer 13

In rodents, birds and soil

Question 14

Usually infects cattle with pneumonia and abortion in cats.

Answer 14

Y. pseudotuberculosis

Question 15

T/F: Pseudotuberculosis common in captive birds

Answer 15

True

Question 16

In guinea pigs:
1. Animals lose weight develop diarrhea and die in ____weeks

Answer 16

3-4 weeks

Question 17

What part are swollen in Y. pseudotuberculosis in guinea pigs?

Answer 17

Mesenteric lymph nodes greatly swollen and caseous, nodular abscesses in Peyer’s patches, liver and spleen

Question 18

What happens during incubation at 37 C in Y.pseudotuberculosis

Answer 18

Incubation at 37’C results in loss of plasmid-encoded V and W antigens and loss of invasive ability

Question 19

What type of parasite is Y. pseudotuberculosis

Answer 19

Facultative intracellular parasite; cell-mediated immunity

Question 20

Diagnosis of Y. pseudotuberculosis?

Answer 20

Differentiated from Y. pestis by urease test and ability to grow well in deoxycholate-citrate agar.

Question 21

Antimicrobial Susceptibility

Answer 21

Sensitive to chloramphenicol, nalidixic acid, streptomycin, sulfonamides and tetracycline

Question 22

T/F: Y. pseudotuberculosis is common in humans?

Answer 22

False: Rare but severe, fatal infections, mesenteric adenitis or septicemia

Question 23

Yersinia that is ubiquitous but isolated from humans and chinchillas with alimentary tract disturbances, from healthy cattle and swine and from meat, shellfish and ice cream

Answer 23

Yersinia enterolitica

Question 24

Yersinia enterolitica heat-stable enterotoxin is produced at?

Answer 24

Heat-stable enterotoxin produced at 30’C

Question 25

What diseases caused by Yersinia enterolitica in humans?

Answer 25

Diseases in humans, terminal ileitis, diarrhea, mesenteric adenitis and symptoms that simulate appendicitis

Question 26

Cause of bubonic plague or black death in humans

Answer 26

Y. pestis

Question 27

Y. pestis in warm climates

Answer 27

assumes bubonic form, swollen lymph nodes known as buboes

Question 28

Y. pestis in cold climates

Answer 28

disease in pneumonic form which is highly fatal and contagious

Question 29

T/F: Y. pestis resembles Y. pseudotuberculosis in microscopic and colonial morphology and antigenic make-up

Answer 29

True

Question 30

Y. pestis multiplies in?

Answer 30

Organism multiplies in flea

Question 31

Y.pestis spreads rapidly

Answer 31

Once introduced into population, spreads rapidly

Question 32

When plague spreads in areas sparsely inhabited by humans

Answer 32

sylvatic form