What are 5 things that Lipids and Fatty Acids do?
1. Store Energy2. Form Membranes3. Carry information and signals (like in inflammation)4. Do other services (vitamins, enzyme cofactors, colorants)5. Surfactants
What does an omega 3 fatty acid mean?
Its a fatty acid chain that has a double bond at the 3rd carbon from the tail end.
What is a linker molecule?
A molecule that attaches to a number of fatty acid chains.
Whats the difference between a glycolipid sphingolipid and a phospholipid sphingolipid?
Both have a sphingosine linker with fatty acid chains, but a glycolipid had a sugar attached to it as well and the phospholipid has a phosphate and choline attached to it.
What is a sterol lipid?
Its characterized by the three- 6 carbon rings and one-5 carbon ring. It has a polar head group and an alkyl side chain.
What is an example of a storage lipid?
What are the 5 main characteristics of a storage lipid?
1. have a glycerol linker2. Saturated, unsaturated, or polyunsaturated3.non-polar4. inert in aqueous solutionsnot found in biological membranes.5. Energy dense
What transfers free fatty acids through the bloodstream?
What transfers triglycerides from adipose tissues to other cells?
What are the 3 major membrane proteins?
1. Phospholipids- attachments to cell membrane2. Sphingolipids3. Glycolipids - cell signaling
What is a phospholipid made of?
glycerol or sphingosine linker, a phosphate group and fatty acids.
What is a membrane sphingolipid made of?
One sphingosine, one fatty acid, and a phosphate, glucose or polysaccharide component.
What is the purpose of a glycolipid?
It is involved in cell identification and also anchors proteins to membranes.
What is cholesterol and what does it do?
It is a membrane sterol. It Increases membrane rigidity, reduces membrane permeability, lipid raft constituent, necessary for endocytosis.
How are lipids involved in inflammation?
Their signaling drives and resolves inflammation.
What are 3 inflammatory lipids?
1. prostaglandins2. thromboxanes3. Leukotrienes
How are inflammatory lipids made?
Enzymes called cyclooxyrgenase 1 and 2 (COX 1/2) produce prostaglandins and thromboxanes from arachidonic acid.
How do NSAIDs help with inflammation?
They block COX 1/2 function from producing inflammatory lipids.
What are the inflammatory lipids called that are part of the immune response?
Eicosanoids that act as vasodilators to signal immune cell response